Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota

Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota

The effects of antibiotics on the gut microbiota can lead to enhanced colonization of Clostridioides difficile (C. difficile) and toxin-mediated pathogenesis. Here, using defined toxin-mutant strains and a murine model, the authors provide insights into how toxin-induced inflammation alters C. diffi...

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Autores principales: Joshua R. Fletcher, Colleen M. Pike, Ruth J. Parsons, Alissa J. Rivera, Matthew H. Foley, Michael R. McLaren, Stephanie A. Montgomery, Casey M. Theriot
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/9e6aa7aed98f489781f33be6a4d04611
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