Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia

To assess the pattern of antibiotic utilization and outcome of patients with bacteremia in a General Medical Ward, all positive blood cultures (BC) over a 12-month period from January 1994 to December 1995 were retrospectively reviewed. Fifty-two positive BC were recorded in 43 patients (63% males,...

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Autores principales:	A Al Shimemeri, H Al Ghadeer, Z Memish
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2011
Materias:	antibiotic medical riyadh saudi arabia utilization Medicine R
Acceso en línea:	https://doaj.org/article/9e6b2040cd484c008d6c999de4bb5846
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spelling	oai:doaj.org-article:9e6b2040cd484c008d6c999de4bb58462021-12-02T17:59:19ZAntibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia2231-07702249-446410.4103/2231-0770.83717https://doaj.org/article/9e6b2040cd484c008d6c999de4bb58462011-07-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/2231-0770.83717https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464To assess the pattern of antibiotic utilization and outcome of patients with bacteremia in a General Medical Ward, all positive blood cultures (BC) over a 12-month period from January 1994 to December 1995 were retrospectively reviewed. Fifty-two positive BC were recorded in 43 patients (63% males, 37% females; mean age 65.9 ± 16.6). 72% of the patients received antibiotics before or soon after obtaining the BC, and ceftriaxone was the most frequently-prescribed antibiotic (41.93%), either alone or in combination with other antibiotics. The bacteremia was due to gram-positive cocci in 60.46% of cases, gram-negative rods in 30.23%, and gram-positive rods in 9.30%. Positive BC due to contamination were not included. The most common gram-positive cocci were Staphylococcus epidermidis, followed by S. aureus, while the most common gram-negative bacilli were Brucella species, Proteus mirabilis, and Klebsiella sp. The suspected sources of the bacteremia were respiratory (21.2%), urinary (19.2%), or skin (19.2%). A subsequent change in the antibiotics regimen was done in 69.76% cases after BC results became available with no apparent effect on the outcome. Adding vancomycin and clindamycin was the most frequent change done (19.4% for each equally). Complications developed in 69.76% of patients, with 88.66% of them suffering from sepsis/shock. 69.23% of the patients improved and 30.77% expired; death was related to infection in 87.5% of cases. In conclusion, most bacteremia in the medical ward of the hospital were due to gram-positive cocci, which should be considered in antibiotic selection prior to BC. Risk factors for acquiring Brucellosis should always be obtained.A Al ShimemeriH Al GhadeerZ MemishThieme Medical and Scientific Publishers Pvt. Ltd.articleantibioticmedicalriyadhsaudi arabiautilizationMedicineRENAvicenna Journal of Medicine, Vol 01, Iss 01, Pp 8-11 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	antibiotic medical riyadh saudi arabia utilization Medicine R
spellingShingle	antibiotic medical riyadh saudi arabia utilization Medicine R A Al Shimemeri H Al Ghadeer Z Memish Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia
description	To assess the pattern of antibiotic utilization and outcome of patients with bacteremia in a General Medical Ward, all positive blood cultures (BC) over a 12-month period from January 1994 to December 1995 were retrospectively reviewed. Fifty-two positive BC were recorded in 43 patients (63% males, 37% females; mean age 65.9 ± 16.6). 72% of the patients received antibiotics before or soon after obtaining the BC, and ceftriaxone was the most frequently-prescribed antibiotic (41.93%), either alone or in combination with other antibiotics. The bacteremia was due to gram-positive cocci in 60.46% of cases, gram-negative rods in 30.23%, and gram-positive rods in 9.30%. Positive BC due to contamination were not included. The most common gram-positive cocci were Staphylococcus epidermidis, followed by S. aureus, while the most common gram-negative bacilli were Brucella species, Proteus mirabilis, and Klebsiella sp. The suspected sources of the bacteremia were respiratory (21.2%), urinary (19.2%), or skin (19.2%). A subsequent change in the antibiotics regimen was done in 69.76% cases after BC results became available with no apparent effect on the outcome. Adding vancomycin and clindamycin was the most frequent change done (19.4% for each equally). Complications developed in 69.76% of patients, with 88.66% of them suffering from sepsis/shock. 69.23% of the patients improved and 30.77% expired; death was related to infection in 87.5% of cases. In conclusion, most bacteremia in the medical ward of the hospital were due to gram-positive cocci, which should be considered in antibiotic selection prior to BC. Risk factors for acquiring Brucellosis should always be obtained.
format	article
author	A Al Shimemeri H Al Ghadeer Z Memish
author_facet	A Al Shimemeri H Al Ghadeer Z Memish
author_sort	A Al Shimemeri
title	Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia
title_short	Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia
title_full	Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia
title_fullStr	Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia
title_full_unstemmed	Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia
title_sort	antibiotic utilization pattern in a general medical ward of a tertiary medical center in saudi arabia
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2011
url	https://doaj.org/article/9e6b2040cd484c008d6c999de4bb5846
work_keys_str_mv	AT aalshimemeri antibioticutilizationpatterninageneralmedicalwardofatertiarymedicalcenterinsaudiarabia AT halghadeer antibioticutilizationpatterninageneralmedicalwardofatertiarymedicalcenterinsaudiarabia AT zmemish antibioticutilizationpatterninageneralmedicalwardofatertiarymedicalcenterinsaudiarabia
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Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia

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