Interaction of PKR with single-stranded RNA
Abstract Although the antiviral kinase PKR was originally characterized as a double-stranded RNA activated enzyme it can be stimulated by RNAs containing limited secondary structure. Single-stranded regions in such RNAs contribute to binding and activation but the mechanism is not understood. Here,...
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Main Authors: | Christopher B. Mayo, James L. Cole |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/9e6d55f8d40d4cf4ba648d3cf513a13b |
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