Interaction of PKR with single-stranded RNA
Abstract Although the antiviral kinase PKR was originally characterized as a double-stranded RNA activated enzyme it can be stimulated by RNAs containing limited secondary structure. Single-stranded regions in such RNAs contribute to binding and activation but the mechanism is not understood. Here,...
Enregistré dans:
Auteurs principaux: | Christopher B. Mayo, James L. Cole |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/9e6d55f8d40d4cf4ba648d3cf513a13b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
PKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs
par: Teresa Cesaro, et autres
Publié: (2021) -
Stress-induced TRBP phosphorylation enhances its interaction with PKR to regulate cellular survival
par: Evelyn Chukwurah, et autres
Publié: (2018) -
The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.
par: Pauline Sebby Ogolla, et autres
Publié: (2013) -
Single-stranded RNA viruses infecting the invasive Argentine ant, Linepithema humile
par: Monica A. M. Gruber, et autres
Publié: (2017) -
Armillaria root rot fungi host single-stranded RNA viruses
par: Riikka Linnakoski, et autres
Publié: (2021)