Interaction of PKR with single-stranded RNA

Abstract Although the antiviral kinase PKR was originally characterized as a double-stranded RNA activated enzyme it can be stimulated by RNAs containing limited secondary structure. Single-stranded regions in such RNAs contribute to binding and activation but the mechanism is not understood. Here,...

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Bibliographic Details
Main Authors: Christopher B. Mayo, James L. Cole
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/9e6d55f8d40d4cf4ba648d3cf513a13b
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