Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies.

Sterile protection against Plasmodium knowlesi in rhesus monkeys from a malaria vaccine: comparison of heterologous prime boost strategies.

Using newer vaccine platforms which have been effective against malaria in rodent models, we tested five immunization regimens against Plasmodium knowlesi in rhesus monkeys. All vaccines included the same four P. knowlesi antigens: the pre-erythrocytic antigens CSP, SSP2, and erythrocytic antigens A...

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Détails bibliographiques
Auteurs principaux: George Jiang, Meng Shi, Solomon Conteh, Nancy Richie, Glenna Banania, Harini Geneshan, Anais Valencia, Priti Singh, Joao Aguiar, Keith Limbach, Kurt I Kamrud, Jonathan Rayner, Jonathan Smith, Joseph T Bruder, C Richter King, Takafumi Tsuboi, Satoru Takeo, Yaeta Endo, Denise L Doolan, Thomas L Richie, Walter R Weiss
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/9e6e88399c3947899ccd9b821b2fadf7
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