SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a.

<h4>Background</h4>Extracellular superoxide dismutase (SOD3), which dismutates superoxide anion to hydrogen peroxide, has been shown to reduce the free radical stress derived apoptosis in tissue injuries. Since both superoxide anion and hydrogen peroxide have a marked impact on signal tr...

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Auteurs principaux: Lilja E Laatikainen, Mariarosaria Incoronato, Maria Domenica Castellone, Juha P Laurila, Massimo Santoro, Mikko O Laukkanen
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/9e7272a3d7eb4c899a8ad02f13cab850
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