Conformational heterogeneity of the calmodulin binding interface
Calmodulin is an important calcium sensor that can recognise and interact with a large range of proteins. Here, the authors use molecular dynamics simulations and Markov state models to show that the range of binding conformations adopted without substrate can help explain its diverse and specific b...
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| Autores principales: | , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2016
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/9e79a6d3f3e04b1184f9366e42aca192 |
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