Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1.

Behavioral characterization of a mouse model overexpressing DSCR1/ RCAN1.

DSCR1/ RCAN1 is a chromosome 21 gene found to be overexpressed in the brains of Down syndrome (DS) and postulated as a good candidate to contribute to mental disability. However, even though Rcan1 knockout mice have pronounced spatial learning and memory deficits, the possible deleterious effects of...

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Autores principales: Mara Dierssen, Gloria Arqué, Jerome McDonald, Nuria Andreu, Carmen Martínez-Cué, Jesús Flórez, Cristina Fillat
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/9e7ed7bf502a4cbc88351f0f74b27a57
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