Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells

Th17 cells can transdifferentiate into regulatory T (Treg) cells. Here the authors characterize tumour-driven Th17-to-Tregcell transdifferentiation and identify potential cancer therapy targets.

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Autores principales:	Stephanie Downs-Canner, Sara Berkey, Greg M. Delgoffe, Robert P. Edwards, Tyler Curiel, Kunle Odunsi, David L. Bartlett, Nataša Obermajer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9e8d4eb2095e4915964c459f3f8ece80
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spelling	oai:doaj.org-article:9e8d4eb2095e4915964c459f3f8ece802021-12-02T14:40:23ZSuppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells10.1038/ncomms146492041-1723https://doaj.org/article/9e8d4eb2095e4915964c459f3f8ece802017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14649https://doaj.org/toc/2041-1723Th17 cells can transdifferentiate into regulatory T (Treg) cells. Here the authors characterize tumour-driven Th17-to-Tregcell transdifferentiation and identify potential cancer therapy targets.Stephanie Downs-CannerSara BerkeyGreg M. DelgoffeRobert P. EdwardsTyler CurielKunle OdunsiDavid L. BartlettNataša ObermajerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephanie Downs-Canner Sara Berkey Greg M. Delgoffe Robert P. Edwards Tyler Curiel Kunle Odunsi David L. Bartlett Nataša Obermajer Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
description	Th17 cells can transdifferentiate into regulatory T (Treg) cells. Here the authors characterize tumour-driven Th17-to-Tregcell transdifferentiation and identify potential cancer therapy targets.
format	article
author	Stephanie Downs-Canner Sara Berkey Greg M. Delgoffe Robert P. Edwards Tyler Curiel Kunle Odunsi David L. Bartlett Nataša Obermajer
author_facet	Stephanie Downs-Canner Sara Berkey Greg M. Delgoffe Robert P. Edwards Tyler Curiel Kunle Odunsi David L. Bartlett Nataša Obermajer
author_sort	Stephanie Downs-Canner
title	Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
title_short	Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
title_full	Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
title_fullStr	Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
title_full_unstemmed	Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells
title_sort	suppressive il-17a+foxp3+ and ex-th17 il-17anegfoxp3+ treg cells are a source of tumour-associated treg cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9e8d4eb2095e4915964c459f3f8ece80
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Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells

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