Upregulation of MicroRNA-146a by Hepatitis B Virus X Protein Contributes to Hepatitis Development by Downregulating Complement Factor H

ABSTRACT Hepatic injuries in hepatitis B virus (HBV) patients are caused by immune responses of the host. In our previous study, microRNA-146a (miR-146a), an innate immunity-related miRNA, and complement factor H (CFH), an important negative regulator of the alternative pathway of complement activat...

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Autores principales: Jun-Feng Li, Xiao-Peng Dai, Wei Zhang, Shi-Hui Sun, Yang Zeng, Guang-Yu Zhao, Zhi-Hua Kou, Yan Guo, Hong Yu, Lan-Ying Du, Shi-Bo Jiang, Yu-Sen Zhou
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/9e8ee89419ea4bed94d42b1fd6bd1589
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