Escherichia coli can survive stress by noisy growth modulation
Noisy gene expression leading to phenotypic variability can help organisms to survive in changing environments. Here, Patange et al. show that noisy expression of a stress response regulator, RpoS, allows E. coli cells to modulate their growth rates to survive future adverse environments.
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Nature Portfolio
2018
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oai:doaj.org-article:9e91aadcaffe440b96bf4b0df8cd6cb82021-12-02T15:33:56ZEscherichia coli can survive stress by noisy growth modulation10.1038/s41467-018-07702-z2041-1723https://doaj.org/article/9e91aadcaffe440b96bf4b0df8cd6cb82018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07702-zhttps://doaj.org/toc/2041-1723Noisy gene expression leading to phenotypic variability can help organisms to survive in changing environments. Here, Patange et al. show that noisy expression of a stress response regulator, RpoS, allows E. coli cells to modulate their growth rates to survive future adverse environments.Om PatangeChristian SchwallMatt JonesCasandra VillavaDouglas A. GriffithAndrew PhillipsJames C. W. LockeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Om Patange Christian Schwall Matt Jones Casandra Villava Douglas A. Griffith Andrew Phillips James C. W. Locke Escherichia coli can survive stress by noisy growth modulation |
description |
Noisy gene expression leading to phenotypic variability can help organisms to survive in changing environments. Here, Patange et al. show that noisy expression of a stress response regulator, RpoS, allows E. coli cells to modulate their growth rates to survive future adverse environments. |
format |
article |
author |
Om Patange Christian Schwall Matt Jones Casandra Villava Douglas A. Griffith Andrew Phillips James C. W. Locke |
author_facet |
Om Patange Christian Schwall Matt Jones Casandra Villava Douglas A. Griffith Andrew Phillips James C. W. Locke |
author_sort |
Om Patange |
title |
Escherichia coli can survive stress by noisy growth modulation |
title_short |
Escherichia coli can survive stress by noisy growth modulation |
title_full |
Escherichia coli can survive stress by noisy growth modulation |
title_fullStr |
Escherichia coli can survive stress by noisy growth modulation |
title_full_unstemmed |
Escherichia coli can survive stress by noisy growth modulation |
title_sort |
escherichia coli can survive stress by noisy growth modulation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/9e91aadcaffe440b96bf4b0df8cd6cb8 |
work_keys_str_mv |
AT ompatange escherichiacolicansurvivestressbynoisygrowthmodulation AT christianschwall escherichiacolicansurvivestressbynoisygrowthmodulation AT mattjones escherichiacolicansurvivestressbynoisygrowthmodulation AT casandravillava escherichiacolicansurvivestressbynoisygrowthmodulation AT douglasagriffith escherichiacolicansurvivestressbynoisygrowthmodulation AT andrewphillips escherichiacolicansurvivestressbynoisygrowthmodulation AT jamescwlocke escherichiacolicansurvivestressbynoisygrowthmodulation |
_version_ |
1718386980411146240 |