Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences

Introduction: Gall bladder carcinoma is not a common disease. The overall prevalence is low worldwide. It is a highly malignant tumor with a poor prognosis. The outcome of gallbladder carcinoma is poor, and the overall 5-year survival rate is less than 5%. The carcinoma gall bladder is 2-6 times mo...

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Autores principales:	Sanjaya Paudyal, Shiva Raj K.C., Shanta Bir Maharjan, Surendra Shah, Niraj Giri
Formato:	article
Lenguaje:	EN
Publicado:	Society of Surgeons of Nepal 2019
Materias:	Extended cholecystectomy Gall bladder carcinoma Radical Cholecystectomy Surgery RD1-811
Acceso en línea:	https://doaj.org/article/9e94498884364d95b4c5e51024b862be
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spelling	oai:doaj.org-article:9e94498884364d95b4c5e51024b862be2021-12-05T19:15:49ZClinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences10.3126/jssn.v22i2.287221815-39842392-4772https://doaj.org/article/9e94498884364d95b4c5e51024b862be2019-12-01T00:00:00Zhttps://www.nepjol.info/index.php/JSSN/article/view/28722https://doaj.org/toc/1815-3984https://doaj.org/toc/2392-4772 Introduction: Gall bladder carcinoma is not a common disease. The overall prevalence is low worldwide. It is a highly malignant tumor with a poor prognosis. The outcome of gallbladder carcinoma is poor, and the overall 5-year survival rate is less than 5%. The carcinoma gall bladder is 2-6 times more common in females compared to males and its incidence increases with increasing age. Aggressive surgical management and preoperative adjuvant therapy have helped to prolong survival in patients with gallbladder cancer. We conducted a study with an aim to evaluate the clinicopathological aspect of the disease in patients of gall bladder cancer managed in our surgical department. Methods: Data were recorded retrospectively by reviewing the charts of the patients who were diagnosed and treated for carcinoma gall bladder in Patan hospital from Aug 2017 to Aug 2019. Results: Thirty patients were included in the study. Twenty (66.7%) were female and ten (33.33%) were males. Age ranged from 36 to 83 years with the median age of presentation at 63.5 yrs. Curative treatment was possible in 43.33% of the patients, among them 12 had radical surgery and one had cholecystectomy alone for the T1a stage. All other (56.6%) required palliative treatment. One patient developed liver metastasis within six months of radical excision. Conclusions: The majority of the patients present with an advanced disease which makes it less chance for curative surgical resection. Since only palliative care is possible in an advanced stage, early detection and curative treatment are advisable. Sanjaya PaudyalShiva Raj K.C.Shanta Bir MaharjanSurendra ShahNiraj GiriSociety of Surgeons of NepalarticleExtended cholecystectomyGall bladder carcinomaRadical CholecystectomySurgeryRD1-811ENJournal of Society of Surgeons of Nepal, Vol 22, Iss 2 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Extended cholecystectomy Gall bladder carcinoma Radical Cholecystectomy Surgery RD1-811
spellingShingle	Extended cholecystectomy Gall bladder carcinoma Radical Cholecystectomy Surgery RD1-811 Sanjaya Paudyal Shiva Raj K.C. Shanta Bir Maharjan Surendra Shah Niraj Giri Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences
description	Introduction: Gall bladder carcinoma is not a common disease. The overall prevalence is low worldwide. It is a highly malignant tumor with a poor prognosis. The outcome of gallbladder carcinoma is poor, and the overall 5-year survival rate is less than 5%. The carcinoma gall bladder is 2-6 times more common in females compared to males and its incidence increases with increasing age. Aggressive surgical management and preoperative adjuvant therapy have helped to prolong survival in patients with gallbladder cancer. We conducted a study with an aim to evaluate the clinicopathological aspect of the disease in patients of gall bladder cancer managed in our surgical department. Methods: Data were recorded retrospectively by reviewing the charts of the patients who were diagnosed and treated for carcinoma gall bladder in Patan hospital from Aug 2017 to Aug 2019. Results: Thirty patients were included in the study. Twenty (66.7%) were female and ten (33.33%) were males. Age ranged from 36 to 83 years with the median age of presentation at 63.5 yrs. Curative treatment was possible in 43.33% of the patients, among them 12 had radical surgery and one had cholecystectomy alone for the T1a stage. All other (56.6%) required palliative treatment. One patient developed liver metastasis within six months of radical excision. Conclusions: The majority of the patients present with an advanced disease which makes it less chance for curative surgical resection. Since only palliative care is possible in an advanced stage, early detection and curative treatment are advisable.
format	article
author	Sanjaya Paudyal Shiva Raj K.C. Shanta Bir Maharjan Surendra Shah Niraj Giri
author_facet	Sanjaya Paudyal Shiva Raj K.C. Shanta Bir Maharjan Surendra Shah Niraj Giri
author_sort	Sanjaya Paudyal
title	Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences
title_short	Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences
title_full	Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences
title_fullStr	Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences
title_full_unstemmed	Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences
title_sort	clinicopathological study of gall bladder carcinoma: our experience from patan hospital, patan academy of health sciences
publisher	Society of Surgeons of Nepal
publishDate	2019
url	https://doaj.org/article/9e94498884364d95b4c5e51024b862be
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Clinicopathological study of gall bladder carcinoma: Our experience from Patan Hospital, Patan Academy of Health Sciences

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