CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS

Objective: To determine the clinical course and outcome of hospitalized pregnant patients with laboratory confirmed SARS CoV-2 (COVID-19) infection. Study Design: Prospective observational study. Place and Duration of Study: Obstetrics Unit of Pak Emirates Military Hospital (PEMH) and Combined...

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Autores principales:	Asma Ansari, Asifa Siraj, Sumaira Khan, Rabiya Akbar, Abeera Choudry, Hafsa Khalil
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2020
Materias:	clinical course covid-19 neonatal pregnancy Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9e9731ae1a75472a884d406f04014be9
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spelling	oai:doaj.org-article:9e9731ae1a75472a884d406f04014be92021-12-02T14:55:07ZCLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS0030-96482411-8842https://doaj.org/article/9e9731ae1a75472a884d406f04014be92020-09-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5339https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To determine the clinical course and outcome of hospitalized pregnant patients with laboratory confirmed SARS CoV-2 (COVID-19) infection. Study Design: Prospective observational study. Place and Duration of Study: Obstetrics Unit of Pak Emirates Military Hospital (PEMH) and Combined Military Hospital (CMH) Rawalpindi, from May 2020 to Jun 2020. Methodology: All patients reporting for childbirth were tested for SARS CoV-2 and those testing positive were included. Demographic and reproductive profile including age, parity, occupation, contact and travel history, period of gestation at diagnosis and mode of delivery where applicable noted. The primary outcome was Virus clearance time and categorization according to severity of disease into asymptomatic, mild, moderate, severe and critical. Comparison was done between presence of co-morbid conditions and symptoms to category of COVID19. Neonatal sample evaluation for SARS CoV-2 was done. Results: Out of the 881 women giving birth 41 (4.6%) tested positive for SARS Cov-2. Majority were asymptomatic 28 (68.3%) followed by mild 08 (19.5%), moderate 04 (9.8%) and severe 01 (2.4%) category. There was significant association of COVID category with presence of symptoms (p-value <0.005) and comorbid (p-value <0.001). Mean virus clearance time was 8.2 ± 1.66 days. During hospital stay 34 (82.9%) delivered. All 34 (100%) of the delivered babies had no evidence of vertical transmission. Conclusion: Pregnant women with COVID-19 infection have nearly comparable clinical course to non-COVID women in this study. There is also no evidence of vertical transmission to the neonate.Asma AnsariAsifa SirajSumaira KhanRabiya AkbarAbeera ChoudryHafsa KhalilArmy Medical College Rawalpindiarticleclinical coursecovid-19neonatalpregnancyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 2, Pp 613-619 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	clinical course covid-19 neonatal pregnancy Medicine R Medicine (General) R5-920
spellingShingle	clinical course covid-19 neonatal pregnancy Medicine R Medicine (General) R5-920 Asma Ansari Asifa Siraj Sumaira Khan Rabiya Akbar Abeera Choudry Hafsa Khalil CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS
description	Objective: To determine the clinical course and outcome of hospitalized pregnant patients with laboratory confirmed SARS CoV-2 (COVID-19) infection. Study Design: Prospective observational study. Place and Duration of Study: Obstetrics Unit of Pak Emirates Military Hospital (PEMH) and Combined Military Hospital (CMH) Rawalpindi, from May 2020 to Jun 2020. Methodology: All patients reporting for childbirth were tested for SARS CoV-2 and those testing positive were included. Demographic and reproductive profile including age, parity, occupation, contact and travel history, period of gestation at diagnosis and mode of delivery where applicable noted. The primary outcome was Virus clearance time and categorization according to severity of disease into asymptomatic, mild, moderate, severe and critical. Comparison was done between presence of co-morbid conditions and symptoms to category of COVID19. Neonatal sample evaluation for SARS CoV-2 was done. Results: Out of the 881 women giving birth 41 (4.6%) tested positive for SARS Cov-2. Majority were asymptomatic 28 (68.3%) followed by mild 08 (19.5%), moderate 04 (9.8%) and severe 01 (2.4%) category. There was significant association of COVID category with presence of symptoms (p-value <0.005) and comorbid (p-value <0.001). Mean virus clearance time was 8.2 ± 1.66 days. During hospital stay 34 (82.9%) delivered. All 34 (100%) of the delivered babies had no evidence of vertical transmission. Conclusion: Pregnant women with COVID-19 infection have nearly comparable clinical course to non-COVID women in this study. There is also no evidence of vertical transmission to the neonate.
format	article
author	Asma Ansari Asifa Siraj Sumaira Khan Rabiya Akbar Abeera Choudry Hafsa Khalil
author_facet	Asma Ansari Asifa Siraj Sumaira Khan Rabiya Akbar Abeera Choudry Hafsa Khalil
author_sort	Asma Ansari
title	CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS
title_short	CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS
title_full	CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS
title_fullStr	CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS
title_full_unstemmed	CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS
title_sort	clinical course of sars cov-2 infection in hospitalised pregnant patients
publisher	Army Medical College Rawalpindi
publishDate	2020
url	https://doaj.org/article/9e9731ae1a75472a884d406f04014be9
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CLINICAL COURSE OF SARS COV-2 INFECTION IN HOSPITALISED PREGNANT PATIENTS

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