AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions

Changes in AMPAR localization can control the strength of synaptic transmission. Here, the authors show that the interactions of TARP γ8 and the AMPAR N-terminal domain work together to regulate receptor accumulation and positioning at the post-synapse of mouse hippocampal CA1 neurons.

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Autores principales: Jake F. Watson, Alexandra Pinggera, Hinze Ho, Ingo H. Greger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9e9af46d449b42a3b228a2f6b64bac22
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