Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

Photothermal therapy can induce an anti-tumour immune response by producing tumour-associated antigens. Here, the authors design a nanoparticle that simultaneously acts as a photothermal agent and an immune-adjuvant and demonstrate the anti-tumour efficacy in combination with anti-CTLA4 therapy in p...

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Autores principales:	Qian Chen, Ligeng Xu, Chao Liang, Chao Wang, Rui Peng, Zhuang Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9e9e6fa3c41a409f8b926964a73429b3
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spelling	oai:doaj.org-article:9e9e6fa3c41a409f8b926964a73429b32021-12-02T14:39:14ZPhotothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy10.1038/ncomms131932041-1723https://doaj.org/article/9e9e6fa3c41a409f8b926964a73429b32016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13193https://doaj.org/toc/2041-1723Photothermal therapy can induce an anti-tumour immune response by producing tumour-associated antigens. Here, the authors design a nanoparticle that simultaneously acts as a photothermal agent and an immune-adjuvant and demonstrate the anti-tumour efficacy in combination with anti-CTLA4 therapy in preclinical murine cancer models.Qian ChenLigeng XuChao LiangChao WangRui PengZhuang LiuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qian Chen Ligeng Xu Chao Liang Chao Wang Rui Peng Zhuang Liu Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
description	Photothermal therapy can induce an anti-tumour immune response by producing tumour-associated antigens. Here, the authors design a nanoparticle that simultaneously acts as a photothermal agent and an immune-adjuvant and demonstrate the anti-tumour efficacy in combination with anti-CTLA4 therapy in preclinical murine cancer models.
format	article
author	Qian Chen Ligeng Xu Chao Liang Chao Wang Rui Peng Zhuang Liu
author_facet	Qian Chen Ligeng Xu Chao Liang Chao Wang Rui Peng Zhuang Liu
author_sort	Qian Chen
title	Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
title_short	Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
title_full	Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
title_fullStr	Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
title_full_unstemmed	Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
title_sort	photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/9e9e6fa3c41a409f8b926964a73429b3
work_keys_str_mv	AT qianchen photothermaltherapywithimmuneadjuvantnanoparticlestogetherwithcheckpointblockadeforeffectivecancerimmunotherapy AT ligengxu photothermaltherapywithimmuneadjuvantnanoparticlestogetherwithcheckpointblockadeforeffectivecancerimmunotherapy AT chaoliang photothermaltherapywithimmuneadjuvantnanoparticlestogetherwithcheckpointblockadeforeffectivecancerimmunotherapy AT chaowang photothermaltherapywithimmuneadjuvantnanoparticlestogetherwithcheckpointblockadeforeffectivecancerimmunotherapy AT ruipeng photothermaltherapywithimmuneadjuvantnanoparticlestogetherwithcheckpointblockadeforeffectivecancerimmunotherapy AT zhuangliu photothermaltherapywithimmuneadjuvantnanoparticlestogetherwithcheckpointblockadeforeffectivecancerimmunotherapy
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Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

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