High affinity associations with α-SNAP enable calcium entry via Orai1 channels.

High affinity associations with α-SNAP enable calcium entry via Orai1 channels.

Molecular steps that activate store-operated calcium entry (SOCE) via Orai channel supramolecular complex remain incompletely defined. We have earlier shown that α-SNAP regulates the on-site functional assembly and calcium selectivity of Orai1 channels. Here we investigate the molecular basis of its...

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Autores principales: Ramanagouda Ramanagoudr-Bhojappa, Yong Miao, Monika Vig
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/9ea790ac24fe427a884293ec325154a3
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