Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation

Graves’ disease is secondary to the presence of anti-thyrotropin receptor antibodies (TRAb), which stimulate thyroid hormones. TRab determination is crucial for etiological diagnosis. The objectives of this study were (i) to compare two methods for determining TRab by chemoluminiscence vs. standard...

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Autores principales: Silvestre Ramona A., Almería Lafuente Alejandro, Jiménez-Mendiguchía Lucía, García-Cano Ana, Romero López Rubén, García-Izquierdo Belén, Pardo de Santayana Cristina, Iglesias Pedro, Diez Juan J., Arribas Gómez Ignacio, Bernabeu-Andreu Francisco A.
Formato: article
Lenguaje:EN
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Publicado: De Gruyter 2021
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Acceso en línea:https://doaj.org/article/9eb1d9b1c9464f879d8bca756b5c74b1
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Sumario:Graves’ disease is secondary to the presence of anti-thyrotropin receptor antibodies (TRAb), which stimulate thyroid hormones. TRab determination is crucial for etiological diagnosis. The objectives of this study were (i) to compare two methods for determining TRab by chemoluminiscence vs. standard TRACE-immunofluorescence; (ii) to determine the diagnostic validity of the three methods.