Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation

Graves’ disease is secondary to the presence of anti-thyrotropin receptor antibodies (TRAb), which stimulate thyroid hormones. TRab determination is crucial for etiological diagnosis. The objectives of this study were (i) to compare two methods for determining TRab by chemoluminiscence vs. standard...

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Autores principales:	Silvestre Ramona A., Almería Lafuente Alejandro, Jiménez-Mendiguchía Lucía, García-Cano Ana, Romero López Rubén, García-Izquierdo Belén, Pardo de Santayana Cristina, Iglesias Pedro, Diez Juan J., Arribas Gómez Ignacio, Bernabeu-Andreu Francisco A.
Formato:	article
Lenguaje:	EN ES
Publicado:	De Gruyter 2021
Materias:	anti-thyrotropin receptor antibodies (trab) chemiluminescence clinical validation graves’ disease immunofluorescence Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/9eb1d9b1c9464f879d8bca756b5c74b1
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spelling	oai:doaj.org-article:9eb1d9b1c9464f879d8bca756b5c74b12021-12-05T14:10:39ZComparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation2628-491X10.1515/almed-2021-0015https://doaj.org/article/9eb1d9b1c9464f879d8bca756b5c74b12021-03-01T00:00:00Zhttps://doi.org/10.1515/almed-2021-0015https://doaj.org/toc/2628-491XGraves’ disease is secondary to the presence of anti-thyrotropin receptor antibodies (TRAb), which stimulate thyroid hormones. TRab determination is crucial for etiological diagnosis. The objectives of this study were (i) to compare two methods for determining TRab by chemoluminiscence vs. standard TRACE-immunofluorescence; (ii) to determine the diagnostic validity of the three methods.Silvestre Ramona A.Almería Lafuente AlejandroJiménez-Mendiguchía LucíaGarcía-Cano AnaRomero López RubénGarcía-Izquierdo BelénPardo de Santayana CristinaIglesias PedroDiez Juan J.Arribas Gómez IgnacioBernabeu-Andreu Francisco A.De Gruyterarticleanti-thyrotropin receptor antibodies (trab)chemiluminescenceclinical validationgraves’ diseaseimmunofluorescenceMedical technologyR855-855.5ENESAdvances in Laboratory Medicine, Vol 2, Iss 2, Pp 221-227 (2021)
institution	DOAJ
collection	DOAJ
language	EN ES
topic	anti-thyrotropin receptor antibodies (trab) chemiluminescence clinical validation graves’ disease immunofluorescence Medical technology R855-855.5
spellingShingle	anti-thyrotropin receptor antibodies (trab) chemiluminescence clinical validation graves’ disease immunofluorescence Medical technology R855-855.5 Silvestre Ramona A. Almería Lafuente Alejandro Jiménez-Mendiguchía Lucía García-Cano Ana Romero López Rubén García-Izquierdo Belén Pardo de Santayana Cristina Iglesias Pedro Diez Juan J. Arribas Gómez Ignacio Bernabeu-Andreu Francisco A. Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation
description	Graves’ disease is secondary to the presence of anti-thyrotropin receptor antibodies (TRAb), which stimulate thyroid hormones. TRab determination is crucial for etiological diagnosis. The objectives of this study were (i) to compare two methods for determining TRab by chemoluminiscence vs. standard TRACE-immunofluorescence; (ii) to determine the diagnostic validity of the three methods.
format	article
author	Silvestre Ramona A. Almería Lafuente Alejandro Jiménez-Mendiguchía Lucía García-Cano Ana Romero López Rubén García-Izquierdo Belén Pardo de Santayana Cristina Iglesias Pedro Diez Juan J. Arribas Gómez Ignacio Bernabeu-Andreu Francisco A.
author_facet	Silvestre Ramona A. Almería Lafuente Alejandro Jiménez-Mendiguchía Lucía García-Cano Ana Romero López Rubén García-Izquierdo Belén Pardo de Santayana Cristina Iglesias Pedro Diez Juan J. Arribas Gómez Ignacio Bernabeu-Andreu Francisco A.
author_sort	Silvestre Ramona A.
title	Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation
title_short	Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation
title_full	Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation
title_fullStr	Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation
title_full_unstemmed	Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation
title_sort	comparison of three methods for determining anti-thyrotropin receptor antibodies (trab) for diagnosis of graves’ disease: a clinical validation
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/9eb1d9b1c9464f879d8bca756b5c74b1
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Comparison of three methods for determining anti-thyrotropin receptor antibodies (TRAb) for diagnosis of Graves’ disease: a clinical validation

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