Biocatalytic trifluoromethylation of unprotected phenols

The introduction of fluorine into organic molecules often requires prefunctionalised molecules or protection of reactive functional groups. Here, the authors report a biocatalytic method for the trifluoromethylation of unprotected phenols under mild conditions.

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Autores principales:	Robert C. Simon, Eduardo Busto, Nina Richter, Verena Resch, Kendall N. Houk, Wolfgang Kroutil
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9ecbf7f3240549eeaf405aee97bb10fe
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spelling	oai:doaj.org-article:9ecbf7f3240549eeaf405aee97bb10fe2021-12-02T15:35:20ZBiocatalytic trifluoromethylation of unprotected phenols10.1038/ncomms133232041-1723https://doaj.org/article/9ecbf7f3240549eeaf405aee97bb10fe2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13323https://doaj.org/toc/2041-1723The introduction of fluorine into organic molecules often requires prefunctionalised molecules or protection of reactive functional groups. Here, the authors report a biocatalytic method for the trifluoromethylation of unprotected phenols under mild conditions.Robert C. SimonEduardo BustoNina RichterVerena ReschKendall N. HoukWolfgang KroutilNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-6 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Robert C. Simon Eduardo Busto Nina Richter Verena Resch Kendall N. Houk Wolfgang Kroutil Biocatalytic trifluoromethylation of unprotected phenols
description	The introduction of fluorine into organic molecules often requires prefunctionalised molecules or protection of reactive functional groups. Here, the authors report a biocatalytic method for the trifluoromethylation of unprotected phenols under mild conditions.
format	article
author	Robert C. Simon Eduardo Busto Nina Richter Verena Resch Kendall N. Houk Wolfgang Kroutil
author_facet	Robert C. Simon Eduardo Busto Nina Richter Verena Resch Kendall N. Houk Wolfgang Kroutil
author_sort	Robert C. Simon
title	Biocatalytic trifluoromethylation of unprotected phenols
title_short	Biocatalytic trifluoromethylation of unprotected phenols
title_full	Biocatalytic trifluoromethylation of unprotected phenols
title_fullStr	Biocatalytic trifluoromethylation of unprotected phenols
title_full_unstemmed	Biocatalytic trifluoromethylation of unprotected phenols
title_sort	biocatalytic trifluoromethylation of unprotected phenols
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/9ecbf7f3240549eeaf405aee97bb10fe
work_keys_str_mv	AT robertcsimon biocatalytictrifluoromethylationofunprotectedphenols AT eduardobusto biocatalytictrifluoromethylationofunprotectedphenols AT ninarichter biocatalytictrifluoromethylationofunprotectedphenols AT verenaresch biocatalytictrifluoromethylationofunprotectedphenols AT kendallnhouk biocatalytictrifluoromethylationofunprotectedphenols AT wolfgangkroutil biocatalytictrifluoromethylationofunprotectedphenols
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Biocatalytic trifluoromethylation of unprotected phenols

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