Biocatalytic trifluoromethylation of unprotected phenols
The introduction of fluorine into organic molecules often requires prefunctionalised molecules or protection of reactive functional groups. Here, the authors report a biocatalytic method for the trifluoromethylation of unprotected phenols under mild conditions.
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Autores principales: | Robert C. Simon, Eduardo Busto, Nina Richter, Verena Resch, Kendall N. Houk, Wolfgang Kroutil |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/9ecbf7f3240549eeaf405aee97bb10fe |
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