CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS
A study of the peculiarities of clinical manifestations and immunity in patients with chronic myeloid leukemia, depending on the stage of disease was made. In patients at admission were more prevalen t shortness of breath, palpitations, lymphadenopathy, hepatomegaly, splenomegaly, hemorrhagic manife...
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| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
Scientific Сentre for Family Health and Human Reproduction Problems
2012
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/9ed3ed4eff7c4963a9a61208fabcd936 |
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| Sumario: | A study of the peculiarities of clinical manifestations and immunity in patients with chronic myeloid leukemia, depending on the stage of disease was made. In patients at admission were more prevalen t shortness of breath, palpitations, lymphadenopathy, hepatomegaly, splenomegaly, hemorrhagic manifestations. Patients diagnosed at any stage had immune disturbances, with the greatest change — in the terminal stage. In patients in an expanded and in the terminal stages T-cell immunodeficiency developed. The peculiarity of the terminal stage was the reduction of NK-cells and B-lymphocytes. |
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