CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS

A study of the peculiarities of clinical manifestations and immunity in patients with chronic myeloid leukemia, depending on the stage of disease was made. In patients at admission were more prevalen t shortness of breath, palpitations, lymphadenopathy, hepatomegaly, splenomegaly, hemorrhagic manife...

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Autor principal:	O. V. Smirnova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	chronic myeloid leukemia immunity Science Q
Acceso en línea:	https://doaj.org/article/9ed3ed4eff7c4963a9a61208fabcd936
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spelling	oai:doaj.org-article:9ed3ed4eff7c4963a9a61208fabcd9362021-11-23T06:14:19ZCHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS2541-94202587-9596https://doaj.org/article/9ed3ed4eff7c4963a9a61208fabcd9362012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/914https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596A study of the peculiarities of clinical manifestations and immunity in patients with chronic myeloid leukemia, depending on the stage of disease was made. In patients at admission were more prevalen t shortness of breath, palpitations, lymphadenopathy, hepatomegaly, splenomegaly, hemorrhagic manifestations. Patients diagnosed at any stage had immune disturbances, with the greatest change — in the terminal stage. In patients in an expanded and in the terminal stages T-cell immunodeficiency developed. The peculiarity of the terminal stage was the reduction of NK-cells and B-lymphocytes.O. V. SmirnovaScientific Сentre for Family Health and Human Reproduction Problemsarticlechronic myeloid leukemiaimmunityScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 185-189 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	chronic myeloid leukemia immunity Science Q
spellingShingle	chronic myeloid leukemia immunity Science Q O. V. Smirnova CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS
description	A study of the peculiarities of clinical manifestations and immunity in patients with chronic myeloid leukemia, depending on the stage of disease was made. In patients at admission were more prevalen t shortness of breath, palpitations, lymphadenopathy, hepatomegaly, splenomegaly, hemorrhagic manifestations. Patients diagnosed at any stage had immune disturbances, with the greatest change — in the terminal stage. In patients in an expanded and in the terminal stages T-cell immunodeficiency developed. The peculiarity of the terminal stage was the reduction of NK-cells and B-lymphocytes.
format	article
author	O. V. Smirnova
author_facet	O. V. Smirnova
author_sort	O. V. Smirnova
title	CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS
title_short	CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS
title_full	CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS
title_fullStr	CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS
title_full_unstemmed	CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS
title_sort	chronic myeloid leukemia - clinical and immunological peculiarities in adult patients
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/9ed3ed4eff7c4963a9a61208fabcd936
work_keys_str_mv	AT ovsmirnova chronicmyeloidleukemiaclinicalandimmunologicalpeculiaritiesinadultpatients
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CHRONIC MYELOID LEUKEMIA - CLINICAL AND IMMUNOLOGICAL PECULIARITIES IN ADULT PATIENTS

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