Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers.

Under normal conditions the brain maintains a delicate balance between inputs of reward seeking controlled by neurons containing the D1-like family of dopamine receptors and inputs of aversion coming from neurons containing the D2-like family of dopamine receptors. Cocaine is able to subvert these b...

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Autores principales:	Gemma Navarro, Estefania Moreno, Jordi Bonaventura, Marc Brugarolas, Daniel Farré, David Aguinaga, Josefa Mallol, Antoni Cortés, Vicent Casadó, Carmen Lluís, Sergi Ferre, Rafael Franco, Enric Canela, Peter J McCormick
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9ed43522cb714fb4bf2d9388cee44c68
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Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers.

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