Obesity and brain illness: from cognitive and psychological evidences to obesity paradox
Vincenzo Monda,1,* Marco La Marra,1,* Raffaella Perrella,2 Giorgio Caviglia,2 Alessandro Iavarone,3 Sergio Chieffi,1 Giovanni Messina,4 Marco Carotenuto,5 Marcellino Monda,1 Antonietta Messina1 1Department of E...
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Dove Medical Press
2017
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oai:doaj.org-article:9ed75a23970d43398a8229a7b639cad12021-12-02T02:44:52ZObesity and brain illness: from cognitive and psychological evidences to obesity paradox1178-7007https://doaj.org/article/9ed75a23970d43398a8229a7b639cad12017-11-01T00:00:00Zhttps://www.dovepress.com/obesity-and-brain-illness-from-cognitive-and-psychological-evidences-t-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Vincenzo Monda,1,* Marco La Marra,1,* Raffaella Perrella,2 Giorgio Caviglia,2 Alessandro Iavarone,3 Sergio Chieffi,1 Giovanni Messina,4 Marco Carotenuto,5 Marcellino Monda,1 Antonietta Messina1 1Department of Experimental Medicine, Section of Human Physiology, University of Campania Luigi Vanvitelli, Naples, Italy; 2Neurological and Stroke Unit, CTO Hospital, AORN ‘‘Ospedali dei Colli’’, Naples, Italy; 3Department of Psychology, University of Campania Luigi Vanvitelli, Naples, Italy; 4Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 5Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy *These authors contributed equally to this work Abstract: Recent findings showed that obesity represents an additional risk factor to developing brain illness such as cognitive impairments and psychopathological disorders. However, some benefits of overweight in the elderly have been identified and an “obesity paradox” has been shown. Currently, it is still unknown how obesity and brain functioning could be linked, and the process by which body fat independently injures cognitive abilities and psychological well-being remains unclear. To establish the independent role of obesity on cognitive abilities and mental health, clarifying the role played by several factors and understanding their interaction is essential. In this review, we discuss the relationship between obesity and brain illness and underline the role played by confounders and other covariates to determine this link. Keywords: obesity, cognitive decline, mood disorders, obesity paradoxMonda VLa Marra MPerrella RCaviglia GIavarone AChieffi SMessina GCarotenuto MMonda MMessina ADove Medical PressarticleObesityCognitive declineMood disordersObesity paradoxSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 10, Pp 473-479 (2017) |
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Obesity Cognitive decline Mood disorders Obesity paradox Specialties of internal medicine RC581-951 |
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Obesity Cognitive decline Mood disorders Obesity paradox Specialties of internal medicine RC581-951 Monda V La Marra M Perrella R Caviglia G Iavarone A Chieffi S Messina G Carotenuto M Monda M Messina A Obesity and brain illness: from cognitive and psychological evidences to obesity paradox |
description |
Vincenzo Monda,1,* Marco La Marra,1,* Raffaella Perrella,2 Giorgio Caviglia,2 Alessandro Iavarone,3 Sergio Chieffi,1 Giovanni Messina,4 Marco Carotenuto,5 Marcellino Monda,1 Antonietta Messina1 1Department of Experimental Medicine, Section of Human Physiology, University of Campania Luigi Vanvitelli, Naples, Italy; 2Neurological and Stroke Unit, CTO Hospital, AORN ‘‘Ospedali dei Colli’’, Naples, Italy; 3Department of Psychology, University of Campania Luigi Vanvitelli, Naples, Italy; 4Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 5Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy *These authors contributed equally to this work Abstract: Recent findings showed that obesity represents an additional risk factor to developing brain illness such as cognitive impairments and psychopathological disorders. However, some benefits of overweight in the elderly have been identified and an “obesity paradox” has been shown. Currently, it is still unknown how obesity and brain functioning could be linked, and the process by which body fat independently injures cognitive abilities and psychological well-being remains unclear. To establish the independent role of obesity on cognitive abilities and mental health, clarifying the role played by several factors and understanding their interaction is essential. In this review, we discuss the relationship between obesity and brain illness and underline the role played by confounders and other covariates to determine this link. Keywords: obesity, cognitive decline, mood disorders, obesity paradox |
format |
article |
author |
Monda V La Marra M Perrella R Caviglia G Iavarone A Chieffi S Messina G Carotenuto M Monda M Messina A |
author_facet |
Monda V La Marra M Perrella R Caviglia G Iavarone A Chieffi S Messina G Carotenuto M Monda M Messina A |
author_sort |
Monda V |
title |
Obesity and brain illness: from cognitive and psychological evidences to obesity paradox |
title_short |
Obesity and brain illness: from cognitive and psychological evidences to obesity paradox |
title_full |
Obesity and brain illness: from cognitive and psychological evidences to obesity paradox |
title_fullStr |
Obesity and brain illness: from cognitive and psychological evidences to obesity paradox |
title_full_unstemmed |
Obesity and brain illness: from cognitive and psychological evidences to obesity paradox |
title_sort |
obesity and brain illness: from cognitive and psychological evidences to obesity paradox |
publisher |
Dove Medical Press |
publishDate |
2017 |
url |
https://doaj.org/article/9ed75a23970d43398a8229a7b639cad1 |
work_keys_str_mv |
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