Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids
With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real...
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Frontiers Media S.A.
2021
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oai:doaj.org-article:9ed938260e1840dab3954cee9d6c8dec2021-12-01T04:32:25ZMagnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids2296-418510.3389/fbioe.2021.779632https://doaj.org/article/9ed938260e1840dab3954cee9d6c8dec2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fbioe.2021.779632/fullhttps://doaj.org/toc/2296-4185With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real-time data of plasma glucose and lipids relying on the motion feedback of mechanical properties. On-demand and programmable speed and direction of the microdimers can be achieved with the judicious adjustment of the external magnetic field, while their velocity and instantaneous postures provide estimation of glucose, cholesterol, and triglycerides concentrations with high temporal accuracy. Numerical simulations reveal the relationship between motility performance and surrounding liquid properties. Such technology presents a point-of-care testing (POCT) approach to adapt to biofluid measurement, which advances the development of microrobotic system in biomedical fields.Shimin YuShimin YuZhongqi SunZhanxiang ZhangZhanxiang ZhangHaoran SunLina LiuWuyi WangMu LiQingsong ZhaoTianlong LiFrontiers Media S.A.articlemagnetic microdimerpoint-of-care testingangle of processionpeak velocityplasma glucoseplasma lipidsBiotechnologyTP248.13-248.65ENFrontiers in Bioengineering and Biotechnology, Vol 9 (2021) |
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magnetic microdimer point-of-care testing angle of procession peak velocity plasma glucose plasma lipids Biotechnology TP248.13-248.65 |
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magnetic microdimer point-of-care testing angle of procession peak velocity plasma glucose plasma lipids Biotechnology TP248.13-248.65 Shimin Yu Shimin Yu Zhongqi Sun Zhanxiang Zhang Zhanxiang Zhang Haoran Sun Lina Liu Wuyi Wang Mu Li Qingsong Zhao Tianlong Li Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids |
description |
With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real-time data of plasma glucose and lipids relying on the motion feedback of mechanical properties. On-demand and programmable speed and direction of the microdimers can be achieved with the judicious adjustment of the external magnetic field, while their velocity and instantaneous postures provide estimation of glucose, cholesterol, and triglycerides concentrations with high temporal accuracy. Numerical simulations reveal the relationship between motility performance and surrounding liquid properties. Such technology presents a point-of-care testing (POCT) approach to adapt to biofluid measurement, which advances the development of microrobotic system in biomedical fields. |
format |
article |
author |
Shimin Yu Shimin Yu Zhongqi Sun Zhanxiang Zhang Zhanxiang Zhang Haoran Sun Lina Liu Wuyi Wang Mu Li Qingsong Zhao Tianlong Li |
author_facet |
Shimin Yu Shimin Yu Zhongqi Sun Zhanxiang Zhang Zhanxiang Zhang Haoran Sun Lina Liu Wuyi Wang Mu Li Qingsong Zhao Tianlong Li |
author_sort |
Shimin Yu |
title |
Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids |
title_short |
Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids |
title_full |
Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids |
title_fullStr |
Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids |
title_full_unstemmed |
Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids |
title_sort |
magnetic microdimer as mobile meter for measuring plasma glucose and lipids |
publisher |
Frontiers Media S.A. |
publishDate |
2021 |
url |
https://doaj.org/article/9ed938260e1840dab3954cee9d6c8dec |
work_keys_str_mv |
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