Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids

With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real...

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Autores principales: Shimin Yu, Zhongqi Sun, Zhanxiang Zhang, Haoran Sun, Lina Liu, Wuyi Wang, Mu Li, Qingsong Zhao, Tianlong Li
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Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/9ed938260e1840dab3954cee9d6c8dec
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spelling oai:doaj.org-article:9ed938260e1840dab3954cee9d6c8dec2021-12-01T04:32:25ZMagnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids2296-418510.3389/fbioe.2021.779632https://doaj.org/article/9ed938260e1840dab3954cee9d6c8dec2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fbioe.2021.779632/fullhttps://doaj.org/toc/2296-4185With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real-time data of plasma glucose and lipids relying on the motion feedback of mechanical properties. On-demand and programmable speed and direction of the microdimers can be achieved with the judicious adjustment of the external magnetic field, while their velocity and instantaneous postures provide estimation of glucose, cholesterol, and triglycerides concentrations with high temporal accuracy. Numerical simulations reveal the relationship between motility performance and surrounding liquid properties. Such technology presents a point-of-care testing (POCT) approach to adapt to biofluid measurement, which advances the development of microrobotic system in biomedical fields.Shimin YuShimin YuZhongqi SunZhanxiang ZhangZhanxiang ZhangHaoran SunLina LiuWuyi WangMu LiQingsong ZhaoTianlong LiFrontiers Media S.A.articlemagnetic microdimerpoint-of-care testingangle of processionpeak velocityplasma glucoseplasma lipidsBiotechnologyTP248.13-248.65ENFrontiers in Bioengineering and Biotechnology, Vol 9 (2021)
institution DOAJ
collection DOAJ
language EN
topic magnetic microdimer
point-of-care testing
angle of procession
peak velocity
plasma glucose
plasma lipids
Biotechnology
TP248.13-248.65
spellingShingle magnetic microdimer
point-of-care testing
angle of procession
peak velocity
plasma glucose
plasma lipids
Biotechnology
TP248.13-248.65
Shimin Yu
Shimin Yu
Zhongqi Sun
Zhanxiang Zhang
Zhanxiang Zhang
Haoran Sun
Lina Liu
Wuyi Wang
Mu Li
Qingsong Zhao
Tianlong Li
Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids
description With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real-time data of plasma glucose and lipids relying on the motion feedback of mechanical properties. On-demand and programmable speed and direction of the microdimers can be achieved with the judicious adjustment of the external magnetic field, while their velocity and instantaneous postures provide estimation of glucose, cholesterol, and triglycerides concentrations with high temporal accuracy. Numerical simulations reveal the relationship between motility performance and surrounding liquid properties. Such technology presents a point-of-care testing (POCT) approach to adapt to biofluid measurement, which advances the development of microrobotic system in biomedical fields.
format article
author Shimin Yu
Shimin Yu
Zhongqi Sun
Zhanxiang Zhang
Zhanxiang Zhang
Haoran Sun
Lina Liu
Wuyi Wang
Mu Li
Qingsong Zhao
Tianlong Li
author_facet Shimin Yu
Shimin Yu
Zhongqi Sun
Zhanxiang Zhang
Zhanxiang Zhang
Haoran Sun
Lina Liu
Wuyi Wang
Mu Li
Qingsong Zhao
Tianlong Li
author_sort Shimin Yu
title Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids
title_short Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids
title_full Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids
title_fullStr Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids
title_full_unstemmed Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids
title_sort magnetic microdimer as mobile meter for measuring plasma glucose and lipids
publisher Frontiers Media S.A.
publishDate 2021
url https://doaj.org/article/9ed938260e1840dab3954cee9d6c8dec
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