Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children

Marian L EvattDepartment of Neurology, Atlanta Veterans Administration Hospital and Emory University School of Medicine, Atlanta, GA, USAAbstract: Excessive drooling may complicate the care of children with chronic neurological conditions by socially isolating both patients and families and by causi...

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Autor principal:	Evatt ML
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/9edea0a757f04b8d9c2a0dd5b758ee23
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spelling	oai:doaj.org-article:9edea0a757f04b8d9c2a0dd5b758ee232021-12-02T02:11:06ZOral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children1176-63281178-2021https://doaj.org/article/9edea0a757f04b8d9c2a0dd5b758ee232011-09-01T00:00:00Zhttp://www.dovepress.com/oral-glycopyrrolate-for-the-treatment-of-chronic-severe-drooling-cause-a8317https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Marian L EvattDepartment of Neurology, Atlanta Veterans Administration Hospital and Emory University School of Medicine, Atlanta, GA, USAAbstract: Excessive drooling may complicate the care of children with chronic neurological conditions by socially isolating both patients and families and by causing secondary dermatitis and infection. Normal control of saliva requires normal integrity of oral structures, normal oropharyngeal sensation, and motor functioning, as well as normal cognitive awareness and rate of salivary production. Glycopyrrolate is an anticholinergic medication with a quaternary structure that recently received Food and Drug Administration approval to treat sialorrhea due to neurological problems in children ages 3&ndash;16 years. This review summarizes the few published studies of safety and efficacy of glycopyrrolate for drooling in children with chronic neurological conditions.Keywords: drooling, sialorrhoea, sialorrhea, children, glycopyrrolateEvatt MLDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2011, Iss Issue 1, Pp 543-547 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Evatt ML Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children
description	Marian L EvattDepartment of Neurology, Atlanta Veterans Administration Hospital and Emory University School of Medicine, Atlanta, GA, USAAbstract: Excessive drooling may complicate the care of children with chronic neurological conditions by socially isolating both patients and families and by causing secondary dermatitis and infection. Normal control of saliva requires normal integrity of oral structures, normal oropharyngeal sensation, and motor functioning, as well as normal cognitive awareness and rate of salivary production. Glycopyrrolate is an anticholinergic medication with a quaternary structure that recently received Food and Drug Administration approval to treat sialorrhea due to neurological problems in children ages 3&ndash;16 years. This review summarizes the few published studies of safety and efficacy of glycopyrrolate for drooling in children with chronic neurological conditions.Keywords: drooling, sialorrhoea, sialorrhea, children, glycopyrrolate
format	article
author	Evatt ML
author_facet	Evatt ML
author_sort	Evatt ML
title	Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children
title_short	Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children
title_full	Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children
title_fullStr	Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children
title_full_unstemmed	Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children
title_sort	oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/9edea0a757f04b8d9c2a0dd5b758ee23
work_keys_str_mv	AT evattml oralglycopyrrolateforthetreatmentofchronicseveredroolingcausedbyneurologicaldisordersinchildren
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Oral glycopyrrolate for the treatment of chronic severe drooling caused by neurological disorders in children

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