Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo

Two-photon laser scanning microscopy allows functional calcium imaging of large neuronal populations in vivo, but the recorded signals typically suffer from low signal to noise. Here the authors develop an algorithm, MLspike, which estimates action potentials from noisy calcium signals, and benchmar...

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Autores principales:	Thomas Deneux, Attila Kaszas, Gergely Szalay, Gergely Katona, Tamás Lakner, Amiram Grinvald, Balázs Rózsa, Ivo Vanzetta
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9eecec08b1ec4791afc90ed8fb9014c7
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spelling	oai:doaj.org-article:9eecec08b1ec4791afc90ed8fb9014c72021-12-02T17:33:08ZAccurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo10.1038/ncomms121902041-1723https://doaj.org/article/9eecec08b1ec4791afc90ed8fb9014c72016-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms12190https://doaj.org/toc/2041-1723Two-photon laser scanning microscopy allows functional calcium imaging of large neuronal populations in vivo, but the recorded signals typically suffer from low signal to noise. Here the authors develop an algorithm, MLspike, which estimates action potentials from noisy calcium signals, and benchmark it against existing methods.Thomas DeneuxAttila KaszasGergely SzalayGergely KatonaTamás LaknerAmiram GrinvaldBalázs RózsaIvo VanzettaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Thomas Deneux Attila Kaszas Gergely Szalay Gergely Katona Tamás Lakner Amiram Grinvald Balázs Rózsa Ivo Vanzetta Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo
description	Two-photon laser scanning microscopy allows functional calcium imaging of large neuronal populations in vivo, but the recorded signals typically suffer from low signal to noise. Here the authors develop an algorithm, MLspike, which estimates action potentials from noisy calcium signals, and benchmark it against existing methods.
format	article
author	Thomas Deneux Attila Kaszas Gergely Szalay Gergely Katona Tamás Lakner Amiram Grinvald Balázs Rózsa Ivo Vanzetta
author_facet	Thomas Deneux Attila Kaszas Gergely Szalay Gergely Katona Tamás Lakner Amiram Grinvald Balázs Rózsa Ivo Vanzetta
author_sort	Thomas Deneux
title	Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo
title_short	Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo
title_full	Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo
title_fullStr	Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo
title_full_unstemmed	Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo
title_sort	accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/9eecec08b1ec4791afc90ed8fb9014c7
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Accurate spike estimation from noisy calcium signals for ultrafast three-dimensional imaging of large neuronal populations in vivo

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