EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY

The aim. was to study peculiarities of ischemic and idiopathic dilated cardiomyopathy and. aggregative activity of thrombocytes and. also the response to the therapy by beta-blockers (Atenolol and Bisoprolol). Material and. methods: study of aggregative activity of thrombocytes in patients with isch...

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Autores principales:	P. N. Isakhanova, Yu. N. Ziyaev
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2012
Materias:	ischemic dilated cardiomyopathy idiopathic dilated cardiomyopathy aggregative activity of thrombocytes beta-adrenoceptor antagonists Science Q
Acceso en línea:	https://doaj.org/article/9eee2aa68acb40be9c58c5f3f475e0fc
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id	oai:doaj.org-article:9eee2aa68acb40be9c58c5f3f475e0fc
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spelling	oai:doaj.org-article:9eee2aa68acb40be9c58c5f3f475e0fc2021-11-23T06:14:21ZEFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY2541-94202587-9596https://doaj.org/article/9eee2aa68acb40be9c58c5f3f475e0fc2012-07-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/962https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The aim. was to study peculiarities of ischemic and idiopathic dilated cardiomyopathy and. aggregative activity of thrombocytes and. also the response to the therapy by beta-blockers (Atenolol and Bisoprolol). Material and. methods: study of aggregative activity of thrombocytes in patients with ischemic and. idiopathic dilated cardiomyopathy, study of dynamics of aggregative activity of thrombocytes in patients with ischemic and. idiopathic dilated cardiomyopathy under the influence of 3-months therapy by Atenolol and. Bisoprolol. Research of aggregative activity of thrombocytes in patients involved in the research demonstrated reliable increase of speed and. maximum amplitude of thrombocytes aggregation at addition of 0,5 normal solution of ADP and. reliabie decrease of time of reaching of maximum amplitude of aggregation. Comparison of patients with idiopathic and. ischemic dilated cardiomyopathy revealed reliable increase of all the indices of aggregative activity in patients with ischemic dilated cardiomyopathy in comparison with ones with idiopathic form in both groups of therapy. The research shows that patients with dilated cardiomyopathy have an activation of aggregative activity of thrombocytes that is more evident in patients with ischemic form. Prolonged use of Bisoprolol allows to achieve more evident antiaggregative effect of used base therapy in comparison with use of Atenolol.P. N. IsakhanovaYu. N. ZiyaevScientific Сentre for Family Health and Human Reproduction Problemsarticleischemic dilated cardiomyopathyidiopathic dilated cardiomyopathyaggregative activity of thrombocytesbeta-adrenoceptor antagonistsScienceQRUActa Biomedica Scientifica, Vol 0, Iss 4(1), Pp 39-43 (2012)
institution	DOAJ
collection	DOAJ
language	RU
topic	ischemic dilated cardiomyopathy idiopathic dilated cardiomyopathy aggregative activity of thrombocytes beta-adrenoceptor antagonists Science Q
spellingShingle	ischemic dilated cardiomyopathy idiopathic dilated cardiomyopathy aggregative activity of thrombocytes beta-adrenoceptor antagonists Science Q P. N. Isakhanova Yu. N. Ziyaev EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY
description	The aim. was to study peculiarities of ischemic and idiopathic dilated cardiomyopathy and. aggregative activity of thrombocytes and. also the response to the therapy by beta-blockers (Atenolol and Bisoprolol). Material and. methods: study of aggregative activity of thrombocytes in patients with ischemic and. idiopathic dilated cardiomyopathy, study of dynamics of aggregative activity of thrombocytes in patients with ischemic and. idiopathic dilated cardiomyopathy under the influence of 3-months therapy by Atenolol and. Bisoprolol. Research of aggregative activity of thrombocytes in patients involved in the research demonstrated reliable increase of speed and. maximum amplitude of thrombocytes aggregation at addition of 0,5 normal solution of ADP and. reliabie decrease of time of reaching of maximum amplitude of aggregation. Comparison of patients with idiopathic and. ischemic dilated cardiomyopathy revealed reliable increase of all the indices of aggregative activity in patients with ischemic dilated cardiomyopathy in comparison with ones with idiopathic form in both groups of therapy. The research shows that patients with dilated cardiomyopathy have an activation of aggregative activity of thrombocytes that is more evident in patients with ischemic form. Prolonged use of Bisoprolol allows to achieve more evident antiaggregative effect of used base therapy in comparison with use of Atenolol.
format	article
author	P. N. Isakhanova Yu. N. Ziyaev
author_facet	P. N. Isakhanova Yu. N. Ziyaev
author_sort	P. N. Isakhanova
title	EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY
title_short	EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY
title_full	EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY
title_fullStr	EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY
title_full_unstemmed	EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY
title_sort	effect of beta-blockers and study of aggregative activity of thrombocytes in patients with dilated cardiomyopathy
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2012
url	https://doaj.org/article/9eee2aa68acb40be9c58c5f3f475e0fc
work_keys_str_mv	AT pnisakhanova effectofbetablockersandstudyofaggregativeactivityofthrombocytesinpatientswithdilatedcardiomyopathy AT yunziyaev effectofbetablockersandstudyofaggregativeactivityofthrombocytesinpatientswithdilatedcardiomyopathy
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EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY

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