Quantitative characterization of 3D bioprinted structural elements under cell generated forces

Advances in biofabrication technology enable 3D printed constructs to resemble real tissues, but it remains unclear how cell-generated forces deform these constructs. Here the authors investigate mechanical behaviours of 3D printed “microbeams” made from mixtures of living cells and extracellular ma...

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Autores principales: Cameron D. Morley, S. Tori Ellison, Tapomoy Bhattacharjee, Christopher S. O’Bryan, Yifan Zhang, Kourtney F. Smith, Christopher P. Kabb, Mathew Sebastian, Ginger L. Moore, Kyle D. Schulze, Sean Niemi, W. Gregory Sawyer, David D. Tran, Duane A. Mitchell, Brent S. Sumerlin, Catherine T. Flores, Thomas E. Angelini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9eef90c4959f4d7aac09a9717b1967dd
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Sumario:Advances in biofabrication technology enable 3D printed constructs to resemble real tissues, but it remains unclear how cell-generated forces deform these constructs. Here the authors investigate mechanical behaviours of 3D printed “microbeams” made from mixtures of living cells and extracellular matrix.