Cholesteatoma fibroblasts promote epithelial cell proliferation through overexpression of epiregulin.

To investigate whether keratinocytes proliferate in response to epiregulin produced by subepithelial fibroblasts derived from middle ear cholesteatoma. Tissue samples were obtained from patients undergoing tympanoplasty. The quantitative polymerase chain reaction and immunohistochemistry were perfor...

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Autores principales: Mamoru Yoshikawa, Hiromi Kojima, Yuichiro Yaguchi, Naoko Okada, Hirohisa Saito, Hiroshi Moriyama
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/9ef2e9bb6f624116886dad6ba649afbd
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