IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY

Objective: To assess the rate of positivity of Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex (TORCH) pathogens in patients suffering from congenital cataract in Pakistan. Study Design: Cross sectional comparative study. Place and Duration of Study: Armed Forces Institute of Ophth...

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Autores principales:	Mamoona Javaid, Hannan Masud, Hassan Sajjad Rathore, Dilshad Ali, Haroon Javaid
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	congenital cataract congenital infections cytomegalovirus herpes simplex virus rubella virus Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9ef37e998fa446919bb2365ae03adf3e
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spelling	oai:doaj.org-article:9ef37e998fa446919bb2365ae03adf3e2021-11-18T02:47:02ZIDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY0030-96482411-8842https://doaj.org/article/9ef37e998fa446919bb2365ae03adf3e2021-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/4320/3563https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To assess the rate of positivity of Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex (TORCH) pathogens in patients suffering from congenital cataract in Pakistan. Study Design: Cross sectional comparative study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Jun 2017 to Mar 2018. Methodology: Cataract group included sixty children already diagnosed with congenital cataract and control group included 60 children not suffering from congenital cataract. Serum samples of all children were collected to test against IgG and IgM antibodies of Toxoplasma gondii, Rubella, Cytomegalo, Herpes simplex pathogens using enzyme linked immune essay (ELISA) technique. Data were analyzed observe in difference between unilateral and bilateral cataract and between cataract and control group. Results: Out of 60 children in cataract group, 29 were tested positive for Toxoplasma gondii, Rubella, Cytomegalo (CMV), Herpes simplex infections. CMV IgG antibodies were identified in 21 (35%) children followed by Rubella IgG 13 (21.7%), Toxoplasmosis IgG 8 (13.3%), CMV IgM 7 (11.7%), HSV I IgG 5 (8.3%), HSV II IgG 2 (3.3%) and HSV I IgM 1 (1.7%) antibodies. None of the children was positive for Toxoplasmosis, Rubella and HSV II IgM antibodies. There was no statistical difference in rate of positivity of Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex pathogens between unilateral and bilateral cataract and between cataract and control group. Conclusion: Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex pathogens are an important cause of congenital cataract with Cytomegalovirus and Rubella virus being most common respectively. In order to prevent paediatric complications, we need........Mamoona JavaidHannan MasudHassan Sajjad RathoreDilshad AliHaroon JavaidArmy Medical College Rawalpindiarticlecongenital cataractcongenital infectionscytomegalovirusherpes simplex virusrubella virusMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 5, Pp 1515-1518 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	congenital cataract congenital infections cytomegalovirus herpes simplex virus rubella virus Medicine R Medicine (General) R5-920
spellingShingle	congenital cataract congenital infections cytomegalovirus herpes simplex virus rubella virus Medicine R Medicine (General) R5-920 Mamoona Javaid Hannan Masud Hassan Sajjad Rathore Dilshad Ali Haroon Javaid IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY
description	Objective: To assess the rate of positivity of Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex (TORCH) pathogens in patients suffering from congenital cataract in Pakistan. Study Design: Cross sectional comparative study. Place and Duration of Study: Armed Forces Institute of Ophthalmology, Rawalpindi, from Jun 2017 to Mar 2018. Methodology: Cataract group included sixty children already diagnosed with congenital cataract and control group included 60 children not suffering from congenital cataract. Serum samples of all children were collected to test against IgG and IgM antibodies of Toxoplasma gondii, Rubella, Cytomegalo, Herpes simplex pathogens using enzyme linked immune essay (ELISA) technique. Data were analyzed observe in difference between unilateral and bilateral cataract and between cataract and control group. Results: Out of 60 children in cataract group, 29 were tested positive for Toxoplasma gondii, Rubella, Cytomegalo (CMV), Herpes simplex infections. CMV IgG antibodies were identified in 21 (35%) children followed by Rubella IgG 13 (21.7%), Toxoplasmosis IgG 8 (13.3%), CMV IgM 7 (11.7%), HSV I IgG 5 (8.3%), HSV II IgG 2 (3.3%) and HSV I IgM 1 (1.7%) antibodies. None of the children was positive for Toxoplasmosis, Rubella and HSV II IgM antibodies. There was no statistical difference in rate of positivity of Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex pathogens between unilateral and bilateral cataract and between cataract and control group. Conclusion: Toxoplasma gondii, Rubella, Cytomegalovirus, Herpes simplex pathogens are an important cause of congenital cataract with Cytomegalovirus and Rubella virus being most common respectively. In order to prevent paediatric complications, we need........
format	article
author	Mamoona Javaid Hannan Masud Hassan Sajjad Rathore Dilshad Ali Haroon Javaid
author_facet	Mamoona Javaid Hannan Masud Hassan Sajjad Rathore Dilshad Ali Haroon Javaid
author_sort	Mamoona Javaid
title	IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY
title_short	IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY
title_full	IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY
title_fullStr	IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY
title_full_unstemmed	IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY
title_sort	identification of torch pathogens in congenital cataract patients visiting armed forces institute of ophthalmology
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/9ef37e998fa446919bb2365ae03adf3e
work_keys_str_mv	AT mamoonajavaid identificationoftorchpathogensincongenitalcataractpatientsvisitingarmedforcesinstituteofophthalmology AT hannanmasud identificationoftorchpathogensincongenitalcataractpatientsvisitingarmedforcesinstituteofophthalmology AT hassansajjadrathore identificationoftorchpathogensincongenitalcataractpatientsvisitingarmedforcesinstituteofophthalmology AT dilshadali identificationoftorchpathogensincongenitalcataractpatientsvisitingarmedforcesinstituteofophthalmology AT haroonjavaid identificationoftorchpathogensincongenitalcataractpatientsvisitingarmedforcesinstituteofophthalmology
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IDENTIFICATION OF TORCH PATHOGENS IN CONGENITAL CATARACT PATIENTS VISITING ARMED FORCES INSTITUTE OF OPHTHALMOLOGY

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