The impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls
Danielle Soares Bio,1 Márcio Gerhardt Soeiro-de-Souza,1 Maria Concepción Garcia Otaduy,2 Rodrigo Machado-Vieira,3 Ricardo Alberto Moreno11Mood Disorders Unit, 2Institute of Radiology, Department and Institute of Psychiatry, School of Medicine, University of São Paulo...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2013
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/9ef3f9dd50da43b78168ef02e7d4f770 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:9ef3f9dd50da43b78168ef02e7d4f770 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:9ef3f9dd50da43b78168ef02e7d4f7702021-12-02T02:45:07ZThe impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls1176-63281178-2021https://doaj.org/article/9ef3f9dd50da43b78168ef02e7d4f7702013-05-01T00:00:00Zhttp://www.dovepress.com/the-impact-of-limbic-system-morphology-on-facial-emotion-recognition-i-a13123https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Danielle Soares Bio,1 Márcio Gerhardt Soeiro-de-Souza,1 Maria Concepción Garcia Otaduy,2 Rodrigo Machado-Vieira,3 Ricardo Alberto Moreno11Mood Disorders Unit, 2Institute of Radiology, Department and Institute of Psychiatry, School of Medicine, University of São Paulo, São Paulo, Brazil; 3Experimental Therapeutics and Pathophysiology Branch (ETPB), National Institute of Mental Health, NIMH NIH, Bethesda, MD, USAIntroduction: Impairments in facial emotion recognition (FER) have been reported in bipolar disorder (BD) subjects during all mood states. This study aims to investigate the impact of limbic system morphology on FER scores in BD subjects and healthy controls.Material and methods: Thirty-nine euthymic BD I (type I) subjects and 40 healthy controls were subjected to a battery of FER tests and examined with 3D structural imaging of the amygdala and hippocampus.Results: The volume of these structures demonstrated a differential pattern of influence on FER scores in BD subjects and controls. In our control sample, larger left and right amygdala demonstrated to be associated to less recognition of sadness faces. In BD group, there was no impact of amygdala volume on FER but we observed a negative impact of the left hippocampus volume in the recognition of happiness while the right hippocampus volume positively impacted on the scores of happiness.Conclusion: Our results indicate that amygdala and hippocampus volumes have distinct effects on FER in BD subjects compared to controls. Knowledge of the neurobiological basis of the illness may help to provide further insights on the role of treatments and psychosocial interventions for BD. Further studies should explore how these effects of amygdala and hippocampus volumes on FER are associated with social networks and social network functioning.Keywords: bipolar disorder, social cognition, facial emotion recognitionBio DSSoeiro-de-Souza MGOtaduy MCGMachado-Vieira RMoreno RADove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 743-751 (2013) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 |
| spellingShingle |
Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Bio DS Soeiro-de-Souza MG Otaduy MCG Machado-Vieira R Moreno RA The impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls |
| description |
Danielle Soares Bio,1 Márcio Gerhardt Soeiro-de-Souza,1 Maria Concepción Garcia Otaduy,2 Rodrigo Machado-Vieira,3 Ricardo Alberto Moreno11Mood Disorders Unit, 2Institute of Radiology, Department and Institute of Psychiatry, School of Medicine, University of São Paulo, São Paulo, Brazil; 3Experimental Therapeutics and Pathophysiology Branch (ETPB), National Institute of Mental Health, NIMH NIH, Bethesda, MD, USAIntroduction: Impairments in facial emotion recognition (FER) have been reported in bipolar disorder (BD) subjects during all mood states. This study aims to investigate the impact of limbic system morphology on FER scores in BD subjects and healthy controls.Material and methods: Thirty-nine euthymic BD I (type I) subjects and 40 healthy controls were subjected to a battery of FER tests and examined with 3D structural imaging of the amygdala and hippocampus.Results: The volume of these structures demonstrated a differential pattern of influence on FER scores in BD subjects and controls. In our control sample, larger left and right amygdala demonstrated to be associated to less recognition of sadness faces. In BD group, there was no impact of amygdala volume on FER but we observed a negative impact of the left hippocampus volume in the recognition of happiness while the right hippocampus volume positively impacted on the scores of happiness.Conclusion: Our results indicate that amygdala and hippocampus volumes have distinct effects on FER in BD subjects compared to controls. Knowledge of the neurobiological basis of the illness may help to provide further insights on the role of treatments and psychosocial interventions for BD. Further studies should explore how these effects of amygdala and hippocampus volumes on FER are associated with social networks and social network functioning.Keywords: bipolar disorder, social cognition, facial emotion recognition |
| format |
article |
| author |
Bio DS Soeiro-de-Souza MG Otaduy MCG Machado-Vieira R Moreno RA |
| author_facet |
Bio DS Soeiro-de-Souza MG Otaduy MCG Machado-Vieira R Moreno RA |
| author_sort |
Bio DS |
| title |
The impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls |
| title_short |
The impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls |
| title_full |
The impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls |
| title_fullStr |
The impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls |
| title_full_unstemmed |
The impact of limbic system morphology on facial emotion recognition in bipolar I disorder and healthy controls |
| title_sort |
impact of limbic system morphology on facial emotion recognition in bipolar i disorder and healthy controls |
| publisher |
Dove Medical Press |
| publishDate |
2013 |
| url |
https://doaj.org/article/9ef3f9dd50da43b78168ef02e7d4f770 |
| work_keys_str_mv |
AT biods theimpactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT soeirodesouzamg theimpactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT otaduymcg theimpactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT machadovieirar theimpactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT morenora theimpactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT biods impactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT soeirodesouzamg impactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT otaduymcg impactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT machadovieirar impactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols AT morenora impactoflimbicsystemmorphologyonfacialemotionrecognitioninbipolaridisorderandhealthycontrols |
| _version_ |
1718402180770168832 |