Plasticity in gustatory and nociceptive neurons controls decision making in C. elegans salt navigation

Martijn Dekkers and Felix Salfelder et al. combine experimental approaches and mathematical modeling to determine the contribution of the two main NaCl sensory neurons (termed ASEL and ASER) and the nociceptive neurons (termed ASH) in C. elegans to the context-dependent switching between NaCl attrac...

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Autores principales: Martijn P. J. Dekkers, Felix Salfelder, Tom Sanders, Oluwatoroti Umuerri, Netta Cohen, Gert Jansen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9ef53957e91646aa9744ce770e66a6cb
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Sumario:Martijn Dekkers and Felix Salfelder et al. combine experimental approaches and mathematical modeling to determine the contribution of the two main NaCl sensory neurons (termed ASEL and ASER) and the nociceptive neurons (termed ASH) in C. elegans to the context-dependent switching between NaCl attraction and avoidance. Their results show that regulated sensitivity of these sensory neurons to NaCl allows the animal to dynamically modulate its behavioral response and suggest a role for sensory modulation in balancing exploration and exploitation during foraging.