Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres

Abstract To assess adherence to standard clinical practice for the diagnosis and treatment of patients undergoing prostate cancer (PCa) radiotherapy in four European countries using clinical audits as part of the international IROCA project. Multi-institutional, retrospective cohort study of 240 ran...

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Autores principales:	Carla Lopes de Castro, Magdalena Fundowicz, Alvar Roselló, Josep Jové, Letizia Deantonio, Artur Aguiar, Carla Pisani, Salvador Villà, Anna Boladeras, Ewelina Konstanty, Marta Kruszyna-Mochalska, Piotr Milecki, Diego Jurado-Bruggeman, Joana Lencart, Ignasi Modolell, Carles Muñoz-Montplet, Luisa Aliste, Maria Gloria Torras, Montserrat Puigdemont, Luísa Carvalho, Marco Krengli, Ferran Guedea, Julian Malicki
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9ef5527922fa492996f94ce5c48756c8
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spelling	oai:doaj.org-article:9ef5527922fa492996f94ce5c48756c82021-12-02T17:34:49ZResults of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres10.1038/s41598-021-91723-02045-2322https://doaj.org/article/9ef5527922fa492996f94ce5c48756c82021-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-91723-0https://doaj.org/toc/2045-2322Abstract To assess adherence to standard clinical practice for the diagnosis and treatment of patients undergoing prostate cancer (PCa) radiotherapy in four European countries using clinical audits as part of the international IROCA project. Multi-institutional, retrospective cohort study of 240 randomly-selected patients treated for PCa (n = 40/centre) in the year 2015 at six European hospitals. Clinical indicators applicable to general and PCa-specific radiotherapy processes were evaluated. All data were obtained directly from medical records. The audits were performed in the year 2017. Adherence to clinical protocols and practices was satisfactory, but with substantial inter-centre variability in numerous variables, as follows: staging MRI (range 27.5–87.5% of cases); presentation to multidisciplinary tumour board (2.5–100%); time elapsed between initial visit to the radiation oncology department and treatment initiation (42–102.5 days); number of treatment interruptions ≥ 1 day (7.5–97.5%). The most common deviation from standard clinical practice was inconsistent data registration, mainly failure to report data related to diagnosis, treatment, and/or adverse events. This clinical audit detected substantial inter-centre variability in adherence to standard clinical practice, most notably inconsistent record keeping. These findings confirm the value of performing clinical audits to detect deviations from standard clinical practices and procedures.Carla Lopes de CastroMagdalena FundowiczAlvar RosellóJosep JovéLetizia DeantonioArtur AguiarCarla PisaniSalvador VillàAnna BoladerasEwelina KonstantyMarta Kruszyna-MochalskaPiotr MileckiDiego Jurado-BruggemanJoana LencartIgnasi ModolellCarles Muñoz-MontpletLuisa AlisteMaria Gloria TorrasMontserrat PuigdemontLuísa CarvalhoMarco KrengliFerran GuedeaJulian MalickiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Carla Lopes de Castro Magdalena Fundowicz Alvar Roselló Josep Jové Letizia Deantonio Artur Aguiar Carla Pisani Salvador Villà Anna Boladeras Ewelina Konstanty Marta Kruszyna-Mochalska Piotr Milecki Diego Jurado-Bruggeman Joana Lencart Ignasi Modolell Carles Muñoz-Montplet Luisa Aliste Maria Gloria Torras Montserrat Puigdemont Luísa Carvalho Marco Krengli Ferran Guedea Julian Malicki Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres
description	Abstract To assess adherence to standard clinical practice for the diagnosis and treatment of patients undergoing prostate cancer (PCa) radiotherapy in four European countries using clinical audits as part of the international IROCA project. Multi-institutional, retrospective cohort study of 240 randomly-selected patients treated for PCa (n = 40/centre) in the year 2015 at six European hospitals. Clinical indicators applicable to general and PCa-specific radiotherapy processes were evaluated. All data were obtained directly from medical records. The audits were performed in the year 2017. Adherence to clinical protocols and practices was satisfactory, but with substantial inter-centre variability in numerous variables, as follows: staging MRI (range 27.5–87.5% of cases); presentation to multidisciplinary tumour board (2.5–100%); time elapsed between initial visit to the radiation oncology department and treatment initiation (42–102.5 days); number of treatment interruptions ≥ 1 day (7.5–97.5%). The most common deviation from standard clinical practice was inconsistent data registration, mainly failure to report data related to diagnosis, treatment, and/or adverse events. This clinical audit detected substantial inter-centre variability in adherence to standard clinical practice, most notably inconsistent record keeping. These findings confirm the value of performing clinical audits to detect deviations from standard clinical practices and procedures.
format	article
author	Carla Lopes de Castro Magdalena Fundowicz Alvar Roselló Josep Jové Letizia Deantonio Artur Aguiar Carla Pisani Salvador Villà Anna Boladeras Ewelina Konstanty Marta Kruszyna-Mochalska Piotr Milecki Diego Jurado-Bruggeman Joana Lencart Ignasi Modolell Carles Muñoz-Montplet Luisa Aliste Maria Gloria Torras Montserrat Puigdemont Luísa Carvalho Marco Krengli Ferran Guedea Julian Malicki
author_facet	Carla Lopes de Castro Magdalena Fundowicz Alvar Roselló Josep Jové Letizia Deantonio Artur Aguiar Carla Pisani Salvador Villà Anna Boladeras Ewelina Konstanty Marta Kruszyna-Mochalska Piotr Milecki Diego Jurado-Bruggeman Joana Lencart Ignasi Modolell Carles Muñoz-Montplet Luisa Aliste Maria Gloria Torras Montserrat Puigdemont Luísa Carvalho Marco Krengli Ferran Guedea Julian Malicki
author_sort	Carla Lopes de Castro
title	Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres
title_short	Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres
title_full	Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres
title_fullStr	Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres
title_full_unstemmed	Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres
title_sort	results of the iroca international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9ef5527922fa492996f94ce5c48756c8
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Results of the IROCA international clinical audit in prostate cancer radiotherapy at six comprehensive cancer centres

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