mTADA is a framework for identifying risk genes from de novo mutations in multiple traits
Joint analysis of multiple traits can increase power and provide insights into shared genetic architecture. Here, Nguyen et al. develop multi-trait TADA (mTADA), an extension of TADA (transmission and de novo association test) that jointly analyses de novo mutations of traits for improved risk-gene...
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Auteurs principaux: | , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/9efa27d972d143f4a615a8a3322d55ba |
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