Pulmonary hypertension in left heart disease

Pulmonary hypertension in left heart disease (PH-LHD) is the most prevalent form of PH. It is classified as group 2 PH as per WHO classification. As the prevalence of left heart disease such as congestive heart failure is increasing, the number of patients with associated PH is rising, coupled with...

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Autores principales: Pratishtha Mehra, Vimal Mehta, Rishi Sukhija, Anjan K. Sinha, Mohit Gupta, M.P. Girish, Wilbert S. Aronow
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Lenguaje:EN
Publicado: Termedia Publishing House 2018
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Acceso en línea:https://doaj.org/article/9eface15fa92451490cd28e394670d79
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spelling oai:doaj.org-article:9eface15fa92451490cd28e394670d792021-12-02T18:39:09ZPulmonary hypertension in left heart disease1734-19221896-915110.5114/aoms.2017.68938https://doaj.org/article/9eface15fa92451490cd28e394670d792018-12-01T00:00:00Zhttps://www.archivesofmedicalscience.com/Pulmonary-hypertension-in-left-heart-disease,65206,0,2.htmlhttps://doaj.org/toc/1734-1922https://doaj.org/toc/1896-9151Pulmonary hypertension in left heart disease (PH-LHD) is the most prevalent form of PH. It is classified as group 2 PH as per WHO classification. As the prevalence of left heart disease such as congestive heart failure is increasing, the number of patients with associated PH is rising, coupled with high morbidity and mortality. Pulmonary hypertension is initially passive or isolated post-capillary (Ipc-PH) due to increased left sided filling pressures. In long standing cases pre-capillary component is added due to development of pulmonary vascular disease, termed combined post- and pre-capillary PH (Cpc-PH) or reactive PH. We describe the hemodynamics, pathophysiology, role of echocardiography and right heart catheterization in PH-LHD. We discuss the significance of PH associated with congestive heart failure as well as valvular heart disease. Although there is no treatment for PH-LHD, we discuss and critically analyze various studies investigating the role of pulmonary vasodilators in this condition. As PH-LHD is an under studied disease, we highlight the areas where further research is required.Pratishtha MehraVimal MehtaRishi SukhijaAnjan K. SinhaMohit GuptaM.P. GirishWilbert S. AronowTermedia Publishing Housearticlepulmonary hypertensionleft heart diseasecongestive heart failurepre-capillarypost-capillarypulmonary artery pressureMedicineRENArchives of Medical Science, Vol 15, Iss 1, Pp 262-273 (2018)
institution DOAJ
collection DOAJ
language EN
topic pulmonary hypertension
left heart disease
congestive heart failure
pre-capillary
post-capillary
pulmonary artery pressure
Medicine
R
spellingShingle pulmonary hypertension
left heart disease
congestive heart failure
pre-capillary
post-capillary
pulmonary artery pressure
Medicine
R
Pratishtha Mehra
Vimal Mehta
Rishi Sukhija
Anjan K. Sinha
Mohit Gupta
M.P. Girish
Wilbert S. Aronow
Pulmonary hypertension in left heart disease
description Pulmonary hypertension in left heart disease (PH-LHD) is the most prevalent form of PH. It is classified as group 2 PH as per WHO classification. As the prevalence of left heart disease such as congestive heart failure is increasing, the number of patients with associated PH is rising, coupled with high morbidity and mortality. Pulmonary hypertension is initially passive or isolated post-capillary (Ipc-PH) due to increased left sided filling pressures. In long standing cases pre-capillary component is added due to development of pulmonary vascular disease, termed combined post- and pre-capillary PH (Cpc-PH) or reactive PH. We describe the hemodynamics, pathophysiology, role of echocardiography and right heart catheterization in PH-LHD. We discuss the significance of PH associated with congestive heart failure as well as valvular heart disease. Although there is no treatment for PH-LHD, we discuss and critically analyze various studies investigating the role of pulmonary vasodilators in this condition. As PH-LHD is an under studied disease, we highlight the areas where further research is required.
format article
author Pratishtha Mehra
Vimal Mehta
Rishi Sukhija
Anjan K. Sinha
Mohit Gupta
M.P. Girish
Wilbert S. Aronow
author_facet Pratishtha Mehra
Vimal Mehta
Rishi Sukhija
Anjan K. Sinha
Mohit Gupta
M.P. Girish
Wilbert S. Aronow
author_sort Pratishtha Mehra
title Pulmonary hypertension in left heart disease
title_short Pulmonary hypertension in left heart disease
title_full Pulmonary hypertension in left heart disease
title_fullStr Pulmonary hypertension in left heart disease
title_full_unstemmed Pulmonary hypertension in left heart disease
title_sort pulmonary hypertension in left heart disease
publisher Termedia Publishing House
publishDate 2018
url https://doaj.org/article/9eface15fa92451490cd28e394670d79
work_keys_str_mv AT pratishthamehra pulmonaryhypertensioninleftheartdisease
AT vimalmehta pulmonaryhypertensioninleftheartdisease
AT rishisukhija pulmonaryhypertensioninleftheartdisease
AT anjanksinha pulmonaryhypertensioninleftheartdisease
AT mohitgupta pulmonaryhypertensioninleftheartdisease
AT mpgirish pulmonaryhypertensioninleftheartdisease
AT wilbertsaronow pulmonaryhypertensioninleftheartdisease
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