Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness

Abstract We tested the effect of different lights as a countermeasure against sleep-loss decrements in alertness, melatonin and cortisol profile, skin temperature and wrist motor activity in healthy young and older volunteers under extendend wakefulness. 26 young [mean (SE): 25.0 (0.6) y)] and 12 ol...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Virginie Gabel, Carolin F. Reichert, Micheline Maire, Christina Schmidt, Luc J. M. Schlangen, Vitaliy Kolodyazhniy, Corrado Garbazza, Christian Cajochen, Antoine U. Viola
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
R
Q
Acceso en línea:https://doaj.org/article/9f011f438f3349308dc9980fec7b24d1
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:9f011f438f3349308dc9980fec7b24d1
record_format dspace
spelling oai:doaj.org-article:9f011f438f3349308dc9980fec7b24d12021-12-02T11:40:32ZDifferential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness10.1038/s41598-017-07060-82045-2322https://doaj.org/article/9f011f438f3349308dc9980fec7b24d12017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-07060-8https://doaj.org/toc/2045-2322Abstract We tested the effect of different lights as a countermeasure against sleep-loss decrements in alertness, melatonin and cortisol profile, skin temperature and wrist motor activity in healthy young and older volunteers under extendend wakefulness. 26 young [mean (SE): 25.0 (0.6) y)] and 12 older participants [(mean (SE): 63.6 (1.3) y)] underwent 40-h of sustained wakefulness during 3 balanced crossover segments, once under dim light (DL: 8 lx), and once under either white light (WL: 250 lx, 2,800 K) or blue-enriched white light (BL: 250 lx, 9,000 K) exposure. Subjective sleepiness, melatonin and cortisol were assessed hourly. Skin temperature and wrist motor activity were continuously recorded. WL and BL induced an alerting response in both the older (p = 0.005) and the young participants (p = 0.021). The evening rise in melatonin was attentuated under both WL and BL only in the young. Cortisol levels were increased and activity levels decreased in the older compared to the young only under BL (p = 0.0003). Compared to the young, both proximal and distal skin temperatures were lower in older participants under all lighting conditions. Thus the color temperature of normal intensity lighting may have differential effects on circadian physiology in young and older individuals.Virginie GabelCarolin F. ReichertMicheline MaireChristina SchmidtLuc J. M. SchlangenVitaliy KolodyazhniyCorrado GarbazzaChristian CajochenAntoine U. ViolaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Virginie Gabel
Carolin F. Reichert
Micheline Maire
Christina Schmidt
Luc J. M. Schlangen
Vitaliy Kolodyazhniy
Corrado Garbazza
Christian Cajochen
Antoine U. Viola
Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
description Abstract We tested the effect of different lights as a countermeasure against sleep-loss decrements in alertness, melatonin and cortisol profile, skin temperature and wrist motor activity in healthy young and older volunteers under extendend wakefulness. 26 young [mean (SE): 25.0 (0.6) y)] and 12 older participants [(mean (SE): 63.6 (1.3) y)] underwent 40-h of sustained wakefulness during 3 balanced crossover segments, once under dim light (DL: 8 lx), and once under either white light (WL: 250 lx, 2,800 K) or blue-enriched white light (BL: 250 lx, 9,000 K) exposure. Subjective sleepiness, melatonin and cortisol were assessed hourly. Skin temperature and wrist motor activity were continuously recorded. WL and BL induced an alerting response in both the older (p = 0.005) and the young participants (p = 0.021). The evening rise in melatonin was attentuated under both WL and BL only in the young. Cortisol levels were increased and activity levels decreased in the older compared to the young only under BL (p = 0.0003). Compared to the young, both proximal and distal skin temperatures were lower in older participants under all lighting conditions. Thus the color temperature of normal intensity lighting may have differential effects on circadian physiology in young and older individuals.
format article
author Virginie Gabel
Carolin F. Reichert
Micheline Maire
Christina Schmidt
Luc J. M. Schlangen
Vitaliy Kolodyazhniy
Corrado Garbazza
Christian Cajochen
Antoine U. Viola
author_facet Virginie Gabel
Carolin F. Reichert
Micheline Maire
Christina Schmidt
Luc J. M. Schlangen
Vitaliy Kolodyazhniy
Corrado Garbazza
Christian Cajochen
Antoine U. Viola
author_sort Virginie Gabel
title Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
title_short Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
title_full Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
title_fullStr Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
title_full_unstemmed Differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
title_sort differential impact in young and older individuals of blue-enriched white light on circadian physiology and alertness during sustained wakefulness
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/9f011f438f3349308dc9980fec7b24d1
work_keys_str_mv AT virginiegabel differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT carolinfreichert differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT michelinemaire differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT christinaschmidt differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT lucjmschlangen differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT vitaliykolodyazhniy differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT corradogarbazza differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT christiancajochen differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
AT antoineuviola differentialimpactinyoungandolderindividualsofblueenrichedwhitelightoncircadianphysiologyandalertnessduringsustainedwakefulness
_version_ 1718395598300774400