ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine

Long-term exposure to nicotine causes a variety of human diseases, such as lung damage/adenocarcinoma, nausea and vomiting, headache, incontinence and heart failure. In this work, as a surface-enhanced Raman scattering (SERS) substrate, zinc oxide (ZnO) tips decorated with gold nanoparticles (AuNPs)...

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Autores principales:	Jiaying Cao, Yan Zhai, Wanxin Tang, Xiaoyu Guo, Ying Wen, Haifeng Yang
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	SERS ZnO tips nicotine AuNPs Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/9f0235054e3b44f488556fd86a899d0b
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spelling	oai:doaj.org-article:9f0235054e3b44f488556fd86a899d0b2021-11-25T16:55:50ZZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine10.3390/bios111104652079-6374https://doaj.org/article/9f0235054e3b44f488556fd86a899d0b2021-11-01T00:00:00Zhttps://www.mdpi.com/2079-6374/11/11/465https://doaj.org/toc/2079-6374Long-term exposure to nicotine causes a variety of human diseases, such as lung damage/adenocarcinoma, nausea and vomiting, headache, incontinence and heart failure. In this work, as a surface-enhanced Raman scattering (SERS) substrate, zinc oxide (ZnO) tips decorated with gold nanoparticles (AuNPs) are fabricated and designated as ZnO/Au. Taking advantage of the synergistic effect of a ZnO semiconductor with morphology of tips and AuNPs, the ZnO/Au-based SERS assay for nicotine demonstrates high sensitivity and the limit of detection 8.9 × 10<sup>−12</sup> mol/L is reached, as well as the corresponding linear dynamic detection range of 10<sup>−10</sup>–10<sup>−6</sup> mol/L. Additionally, the signal reproducibility offered by the SERS substrate could realize the reliable determination of trace nicotine in saliva.Jiaying CaoYan ZhaiWanxin TangXiaoyu GuoYing WenHaifeng YangMDPI AGarticleSERSZnO tipsnicotineAuNPsBiotechnologyTP248.13-248.65ENBiosensors, Vol 11, Iss 465, p 465 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	SERS ZnO tips nicotine AuNPs Biotechnology TP248.13-248.65
spellingShingle	SERS ZnO tips nicotine AuNPs Biotechnology TP248.13-248.65 Jiaying Cao Yan Zhai Wanxin Tang Xiaoyu Guo Ying Wen Haifeng Yang ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
description	Long-term exposure to nicotine causes a variety of human diseases, such as lung damage/adenocarcinoma, nausea and vomiting, headache, incontinence and heart failure. In this work, as a surface-enhanced Raman scattering (SERS) substrate, zinc oxide (ZnO) tips decorated with gold nanoparticles (AuNPs) are fabricated and designated as ZnO/Au. Taking advantage of the synergistic effect of a ZnO semiconductor with morphology of tips and AuNPs, the ZnO/Au-based SERS assay for nicotine demonstrates high sensitivity and the limit of detection 8.9 × 10<sup>−12</sup> mol/L is reached, as well as the corresponding linear dynamic detection range of 10<sup>−10</sup>–10<sup>−6</sup> mol/L. Additionally, the signal reproducibility offered by the SERS substrate could realize the reliable determination of trace nicotine in saliva.
format	article
author	Jiaying Cao Yan Zhai Wanxin Tang Xiaoyu Guo Ying Wen Haifeng Yang
author_facet	Jiaying Cao Yan Zhai Wanxin Tang Xiaoyu Guo Ying Wen Haifeng Yang
author_sort	Jiaying Cao
title	ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
title_short	ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
title_full	ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
title_fullStr	ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
title_full_unstemmed	ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine
title_sort	zno tips dotted with au nanoparticles—advanced sers determination of trace nicotine
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/9f0235054e3b44f488556fd86a899d0b
work_keys_str_mv	AT jiayingcao znotipsdottedwithaunanoparticlesadvancedsersdeterminationoftracenicotine AT yanzhai znotipsdottedwithaunanoparticlesadvancedsersdeterminationoftracenicotine AT wanxintang znotipsdottedwithaunanoparticlesadvancedsersdeterminationoftracenicotine AT xiaoyuguo znotipsdottedwithaunanoparticlesadvancedsersdeterminationoftracenicotine AT yingwen znotipsdottedwithaunanoparticlesadvancedsersdeterminationoftracenicotine AT haifengyang znotipsdottedwithaunanoparticlesadvancedsersdeterminationoftracenicotine
_version_	1718412854443376640

ZnO Tips Dotted with Au Nanoparticles—Advanced SERS Determination of Trace Nicotine

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