How changes in extracellular matrix mechanics and gene expression variability might combine to drive cancer progression.

Changes in extracellular matrix (ECM) structure or mechanics can actively drive cancer progression; however, the underlying mechanism remains unknown. Here we explore whether this process could be mediated by changes in cell shape that lead to increases in genetic noise, given that both factors have...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Justin Werfel, Silva Krause, Ashley G Bischof, Robert J Mannix, Heather Tobin, Yaneer Bar-Yam, Robert M Bellin, Donald E Ingber
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
R
Q
Acceso en línea:https://doaj.org/article/9f06e57e54424523ac945a502435ac64
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares