Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents

Abstract Host–microbe interactions within the gastrointestinal tract (GIT) play a pivotal role in shaping host physiology, ecology, and life history. However, these interactions vary across gut regions due to changes in the physical environment or host immune system activity, thereby altering the mi...

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Autores principales: Jason L. Anders, Mohamed Abdallah Mohamed Moustafa, Wessam Mohamed Ahmed Mohamed, Takashi Hayakawa, Ryo Nakao, Itsuro Koizumi
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9f0abdb75d0942349d7c3fd2dcd30f6d
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spelling oai:doaj.org-article:9f0abdb75d0942349d7c3fd2dcd30f6d2021-12-02T18:07:52ZComparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents10.1038/s41598-021-99379-62045-2322https://doaj.org/article/9f0abdb75d0942349d7c3fd2dcd30f6d2021-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-99379-6https://doaj.org/toc/2045-2322Abstract Host–microbe interactions within the gastrointestinal tract (GIT) play a pivotal role in shaping host physiology, ecology, and life history. However, these interactions vary across gut regions due to changes in the physical environment or host immune system activity, thereby altering the microbial community. Each animal species may harbor their own unique microbial community due to host species-specific ecological traits such as dietary habits, micro-habitat preferences, and mating behavior as well as physiological traits. While the gut microbiota in wild animals has received much attention over the last decade, most studies comparing closely related species only utilized fecal or colon samples. In this study, we first compared the gut microbial community from the small intestine, cecum, colon, and rectum within three sympatric species of wild rodents (i.e. Apodemus speciosus, A. argenteus, and Myodes rufocanus). We then compared each gut region among host species to determine the effect of both gut region and host species on the gut microbiota. We found that the small intestine harbored a unique microbiome as compared to the lower GIT in all three host species, with the genus Lactobacillus in particular having higher abundance in the small intestine of all three host species. There were clear interspecific differences in the microbiome within all gut regions, although some similarity in alpha diversity and community structure within the small intestine was found. Finally, fecal samples may be appropriate for studying the lower GIT in these species, but not the small intestine.Jason L. AndersMohamed Abdallah Mohamed MoustafaWessam Mohamed Ahmed MohamedTakashi HayakawaRyo NakaoItsuro KoizumiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Jason L. Anders
Mohamed Abdallah Mohamed Moustafa
Wessam Mohamed Ahmed Mohamed
Takashi Hayakawa
Ryo Nakao
Itsuro Koizumi
Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents
description Abstract Host–microbe interactions within the gastrointestinal tract (GIT) play a pivotal role in shaping host physiology, ecology, and life history. However, these interactions vary across gut regions due to changes in the physical environment or host immune system activity, thereby altering the microbial community. Each animal species may harbor their own unique microbial community due to host species-specific ecological traits such as dietary habits, micro-habitat preferences, and mating behavior as well as physiological traits. While the gut microbiota in wild animals has received much attention over the last decade, most studies comparing closely related species only utilized fecal or colon samples. In this study, we first compared the gut microbial community from the small intestine, cecum, colon, and rectum within three sympatric species of wild rodents (i.e. Apodemus speciosus, A. argenteus, and Myodes rufocanus). We then compared each gut region among host species to determine the effect of both gut region and host species on the gut microbiota. We found that the small intestine harbored a unique microbiome as compared to the lower GIT in all three host species, with the genus Lactobacillus in particular having higher abundance in the small intestine of all three host species. There were clear interspecific differences in the microbiome within all gut regions, although some similarity in alpha diversity and community structure within the small intestine was found. Finally, fecal samples may be appropriate for studying the lower GIT in these species, but not the small intestine.
format article
author Jason L. Anders
Mohamed Abdallah Mohamed Moustafa
Wessam Mohamed Ahmed Mohamed
Takashi Hayakawa
Ryo Nakao
Itsuro Koizumi
author_facet Jason L. Anders
Mohamed Abdallah Mohamed Moustafa
Wessam Mohamed Ahmed Mohamed
Takashi Hayakawa
Ryo Nakao
Itsuro Koizumi
author_sort Jason L. Anders
title Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents
title_short Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents
title_full Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents
title_fullStr Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents
title_full_unstemmed Comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents
title_sort comparing the gut microbiome along the gastrointestinal tract of three sympatric species of wild rodents
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/9f0abdb75d0942349d7c3fd2dcd30f6d
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