Knockout Serum Replacement as a Substitute for Exosome Free Serum

Exosomes, extracellular vesicles secreted from cells, are carriers containing proteins, lipids, and nucleic acids. By adhering and releasing their contents to the recipient cells, exosomes play a major role in cellular communication. Based on a variety of their originated cells, cargos, and physiolo...

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Autor principal:	Keykavos Gholami
Formato:	article
Lenguaje:	EN
Publicado:	Urology Research Center 2021
Materias:	exosome fetal bovine serum knockout serum replacement purification Diseases of the genitourinary system. Urology RC870-923
Acceso en línea:	https://doaj.org/article/9f14a9c949354b1baf69444a8b85606c
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id	oai:doaj.org-article:9f14a9c949354b1baf69444a8b85606c
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spelling	oai:doaj.org-article:9f14a9c949354b1baf69444a8b85606c2021-11-27T05:25:35ZKnockout Serum Replacement as a Substitute for Exosome Free Serum10.22034/TRU.2020.262287.10562717-042Xhttps://doaj.org/article/9f14a9c949354b1baf69444a8b85606c2021-02-01T00:00:00Zhttps://www.transresurology.com/article_121000.htmlhttps://doaj.org/toc/2717-042XExosomes, extracellular vesicles secreted from cells, are carriers containing proteins, lipids, and nucleic acids. By adhering and releasing their contents to the recipient cells, exosomes play a major role in cellular communication. Based on a variety of their originated cells, cargos, and physiologic state of releasing cell, Exosomes have been attributed an extended range of roles such as signal transduction, reprogramming, epigenetic modification, and inflammation. Recently, it has been shown that exosomes are also involved in pathological mechanisms of diseases, such as neurodegenerative diseases, tumors, chronic inflammation, and cardiovascular diseases. Moreover, exosomes have been used as diagnostic markers for different diseases since their cargos and contents can reflect the physiological or pathological processes of the cells of origin. Because of having features of being carriers, they can be considered as a vehicle to drug delivery or gene therapy.Keykavos GholamiUrology Research Centerarticleexosomefetal bovine serumknockout serum replacementpurificationDiseases of the genitourinary system. UrologyRC870-923ENTranslational Research in Urology, Vol 3, Iss 1, Pp 1-3 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	exosome fetal bovine serum knockout serum replacement purification Diseases of the genitourinary system. Urology RC870-923
spellingShingle	exosome fetal bovine serum knockout serum replacement purification Diseases of the genitourinary system. Urology RC870-923 Keykavos Gholami Knockout Serum Replacement as a Substitute for Exosome Free Serum
description	Exosomes, extracellular vesicles secreted from cells, are carriers containing proteins, lipids, and nucleic acids. By adhering and releasing their contents to the recipient cells, exosomes play a major role in cellular communication. Based on a variety of their originated cells, cargos, and physiologic state of releasing cell, Exosomes have been attributed an extended range of roles such as signal transduction, reprogramming, epigenetic modification, and inflammation. Recently, it has been shown that exosomes are also involved in pathological mechanisms of diseases, such as neurodegenerative diseases, tumors, chronic inflammation, and cardiovascular diseases. Moreover, exosomes have been used as diagnostic markers for different diseases since their cargos and contents can reflect the physiological or pathological processes of the cells of origin. Because of having features of being carriers, they can be considered as a vehicle to drug delivery or gene therapy.
format	article
author	Keykavos Gholami
author_facet	Keykavos Gholami
author_sort	Keykavos Gholami
title	Knockout Serum Replacement as a Substitute for Exosome Free Serum
title_short	Knockout Serum Replacement as a Substitute for Exosome Free Serum
title_full	Knockout Serum Replacement as a Substitute for Exosome Free Serum
title_fullStr	Knockout Serum Replacement as a Substitute for Exosome Free Serum
title_full_unstemmed	Knockout Serum Replacement as a Substitute for Exosome Free Serum
title_sort	knockout serum replacement as a substitute for exosome free serum
publisher	Urology Research Center
publishDate	2021
url	https://doaj.org/article/9f14a9c949354b1baf69444a8b85606c
work_keys_str_mv	AT keykavosgholami knockoutserumreplacementasasubstituteforexosomefreeserum
_version_	1718409246481055744

Knockout Serum Replacement as a Substitute for Exosome Free Serum

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