Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip

In 2018, the world of functional mitral regurgitation changed with the presentation of two trials – Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation (MITRA-FR) and Cardiovascular Outcomes Assessment of the MitraClip Percuta...

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Autores principales:	Kimberly Atianzar, Ming Zhang, Zachary Newhart, Sameer Gafoor
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2019
Materias:	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/9f2921249acb40c893f2e75df11586de
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spelling	oai:doaj.org-article:9f2921249acb40c893f2e75df11586de2021-12-04T16:00:56ZWhy Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip10.15420/icr.2018.40.11756-14851756-1477https://doaj.org/article/9f2921249acb40c893f2e75df11586de2019-01-01T00:00:00Zhttps://www.icrjournal.com/articleindex/icr.2018.40.1https://doaj.org/toc/1756-1477https://doaj.org/toc/1756-1485In 2018, the world of functional mitral regurgitation changed with the presentation of two trials – Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation (MITRA-FR) and Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT). The trials, which seemed to point in two different directions, raised significant questions for the field. This article looks at the differences in effective regurgitant area, guideline-directed medical therapy, patient selection, technical clues and other reasons why the trials had similar aims but very different findings.Kimberly AtianzarMing ZhangZachary NewhartSameer GafoorRadcliffe Medical MediaarticleSurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENInterventional Cardiology: Reviews, Research, Resources, Vol 14, Iss 1, Pp 45-47 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 Kimberly Atianzar Ming Zhang Zachary Newhart Sameer Gafoor Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip
description	In 2018, the world of functional mitral regurgitation changed with the presentation of two trials – Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation (MITRA-FR) and Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral Regurgitation (COAPT). The trials, which seemed to point in two different directions, raised significant questions for the field. This article looks at the differences in effective regurgitant area, guideline-directed medical therapy, patient selection, technical clues and other reasons why the trials had similar aims but very different findings.
format	article
author	Kimberly Atianzar Ming Zhang Zachary Newhart Sameer Gafoor
author_facet	Kimberly Atianzar Ming Zhang Zachary Newhart Sameer Gafoor
author_sort	Kimberly Atianzar
title	Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip
title_short	Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip
title_full	Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip
title_fullStr	Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip
title_full_unstemmed	Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip
title_sort	why did coapt win while mitra-fr failed? defining the appropriate patient population for mitraclip
publisher	Radcliffe Medical Media
publishDate	2019
url	https://doaj.org/article/9f2921249acb40c893f2e75df11586de
work_keys_str_mv	AT kimberlyatianzar whydidcoaptwinwhilemitrafrfaileddefiningtheappropriatepatientpopulationformitraclip AT mingzhang whydidcoaptwinwhilemitrafrfaileddefiningtheappropriatepatientpopulationformitraclip AT zacharynewhart whydidcoaptwinwhilemitrafrfaileddefiningtheappropriatepatientpopulationformitraclip AT sameergafoor whydidcoaptwinwhilemitrafrfaileddefiningtheappropriatepatientpopulationformitraclip
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Why Did COAPT Win While MITRA-FR Failed? Defining the Appropriate Patient Population for MitraClip

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