DNA repair inhibitors sensitize cells differently to high and low LET radiation

Abstract The aim of this study was to investigate effects of high LET α-radiation in combination with inhibitors of DDR (DNA-PK and ATM) and to compare the effect with the radiosensitizing effect of low LET X-ray radiation. The various cell lines were irradiated with α-radiation and with X-ray. Clon...

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Autores principales: Kristina Bannik, Balázs Madas, Sabrina Jarke, Andreas Sutter, Gerhard Siemeister, Christoph Schatz, Dominik Mumberg, Sabine Zitzmann-Kolbe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9f2aae56817c41d6985e4f6c67f4daba
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