Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci

Alternative splicing of mRNAs occurs in tissue specific manners and may be modulated by genetic variations. Here, Takata and colleagues perform splicing quantitative trait loci analysis (sQTL) of human brain and show significant enrichment of sQTLs among neurological disease-associated loci.

Guardado en:

Detalles Bibliográficos
Autores principales:	Atsushi Takata, Naomichi Matsumoto, Tadafumi Kato
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9f2cd71594fe4354b29b139974bf0795
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9f2cd71594fe4354b29b139974bf0795
record_format	dspace
spelling	oai:doaj.org-article:9f2cd71594fe4354b29b139974bf07952021-12-02T17:06:16ZGenome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci10.1038/ncomms145192041-1723https://doaj.org/article/9f2cd71594fe4354b29b139974bf07952017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14519https://doaj.org/toc/2041-1723Alternative splicing of mRNAs occurs in tissue specific manners and may be modulated by genetic variations. Here, Takata and colleagues perform splicing quantitative trait loci analysis (sQTL) of human brain and show significant enrichment of sQTLs among neurological disease-associated loci.Atsushi TakataNaomichi MatsumotoTadafumi KatoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Atsushi Takata Naomichi Matsumoto Tadafumi Kato Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
description	Alternative splicing of mRNAs occurs in tissue specific manners and may be modulated by genetic variations. Here, Takata and colleagues perform splicing quantitative trait loci analysis (sQTL) of human brain and show significant enrichment of sQTLs among neurological disease-associated loci.
format	article
author	Atsushi Takata Naomichi Matsumoto Tadafumi Kato
author_facet	Atsushi Takata Naomichi Matsumoto Tadafumi Kato
author_sort	Atsushi Takata
title	Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
title_short	Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
title_full	Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
title_fullStr	Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
title_full_unstemmed	Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci
title_sort	genome-wide identification of splicing qtls in the human brain and their enrichment among schizophrenia-associated loci
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9f2cd71594fe4354b29b139974bf0795
work_keys_str_mv	AT atsushitakata genomewideidentificationofsplicingqtlsinthehumanbrainandtheirenrichmentamongschizophreniaassociatedloci AT naomichimatsumoto genomewideidentificationofsplicingqtlsinthehumanbrainandtheirenrichmentamongschizophreniaassociatedloci AT tadafumikato genomewideidentificationofsplicingqtlsinthehumanbrainandtheirenrichmentamongschizophreniaassociatedloci
_version_	1718381690441695232

Genome-wide identification of splicing QTLs in the human brain and their enrichment among schizophrenia-associated loci

Ejemplares similares