Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2).

Homeodomain-interacting protein kinase 2 (HIPK2) is a Ser/Thr kinase controlling cell proliferation and survival, whose investigation has been hampered by the lack of specific inhibitors able to dissect its cellular functions. SB203580, a p38 MAP kinase inhibitor, has been used as a tool to inhibit...

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Autores principales: Giorgio Cozza, Sofia Zanin, Renate Determann, Maria Ruzzene, Conrad Kunick, Lorenzo A Pinna
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/9f305def2de64cbbae738c68cd18ff17
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