Synthesis and properties of a selective inhibitor of homeodomain-interacting protein kinase 2 (HIPK2).
Homeodomain-interacting protein kinase 2 (HIPK2) is a Ser/Thr kinase controlling cell proliferation and survival, whose investigation has been hampered by the lack of specific inhibitors able to dissect its cellular functions. SB203580, a p38 MAP kinase inhibitor, has been used as a tool to inhibit...
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Autores principales: | Giorgio Cozza, Sofia Zanin, Renate Determann, Maria Ruzzene, Conrad Kunick, Lorenzo A Pinna |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/9f305def2de64cbbae738c68cd18ff17 |
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