Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG

Lipopolysaccharides (LPS) are synthesized at the periplasmic side of the inner membrane of Gram-negative bacteria and are then extracted by the LptB2FG complex during the first step of LPS transport to the outer membrane. Here the authors present the LptB2FG structure, which supports an alternating...

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Autores principales: Haohao Dong, Zhengyu Zhang, Xiaodi Tang, Neil G. Paterson, Changjiang Dong
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9f348f6efa4b41969dce2efed310a489
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spelling oai:doaj.org-article:9f348f6efa4b41969dce2efed310a4892021-12-02T10:48:28ZStructural and functional insights into the lipopolysaccharide ABC transporter LptB2FG10.1038/s41467-017-00273-52041-1723https://doaj.org/article/9f348f6efa4b41969dce2efed310a4892017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00273-5https://doaj.org/toc/2041-1723Lipopolysaccharides (LPS) are synthesized at the periplasmic side of the inner membrane of Gram-negative bacteria and are then extracted by the LptB2FG complex during the first step of LPS transport to the outer membrane. Here the authors present the LptB2FG structure, which supports an alternating lateral access mechanism for LPS extraction.Haohao DongZhengyu ZhangXiaodi TangNeil G. PatersonChangjiang DongNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Haohao Dong
Zhengyu Zhang
Xiaodi Tang
Neil G. Paterson
Changjiang Dong
Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
description Lipopolysaccharides (LPS) are synthesized at the periplasmic side of the inner membrane of Gram-negative bacteria and are then extracted by the LptB2FG complex during the first step of LPS transport to the outer membrane. Here the authors present the LptB2FG structure, which supports an alternating lateral access mechanism for LPS extraction.
format article
author Haohao Dong
Zhengyu Zhang
Xiaodi Tang
Neil G. Paterson
Changjiang Dong
author_facet Haohao Dong
Zhengyu Zhang
Xiaodi Tang
Neil G. Paterson
Changjiang Dong
author_sort Haohao Dong
title Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
title_short Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
title_full Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
title_fullStr Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
title_full_unstemmed Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
title_sort structural and functional insights into the lipopolysaccharide abc transporter lptb2fg
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/9f348f6efa4b41969dce2efed310a489
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AT xiaoditang structuralandfunctionalinsightsintothelipopolysaccharideabctransporterlptb2fg
AT neilgpaterson structuralandfunctionalinsightsintothelipopolysaccharideabctransporterlptb2fg
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