Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
Lipopolysaccharides (LPS) are synthesized at the periplasmic side of the inner membrane of Gram-negative bacteria and are then extracted by the LptB2FG complex during the first step of LPS transport to the outer membrane. Here the authors present the LptB2FG structure, which supports an alternating...
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Nature Portfolio
2017
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oai:doaj.org-article:9f348f6efa4b41969dce2efed310a4892021-12-02T10:48:28ZStructural and functional insights into the lipopolysaccharide ABC transporter LptB2FG10.1038/s41467-017-00273-52041-1723https://doaj.org/article/9f348f6efa4b41969dce2efed310a4892017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00273-5https://doaj.org/toc/2041-1723Lipopolysaccharides (LPS) are synthesized at the periplasmic side of the inner membrane of Gram-negative bacteria and are then extracted by the LptB2FG complex during the first step of LPS transport to the outer membrane. Here the authors present the LptB2FG structure, which supports an alternating lateral access mechanism for LPS extraction.Haohao DongZhengyu ZhangXiaodi TangNeil G. PatersonChangjiang DongNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Haohao Dong Zhengyu Zhang Xiaodi Tang Neil G. Paterson Changjiang Dong Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG |
description |
Lipopolysaccharides (LPS) are synthesized at the periplasmic side of the inner membrane of Gram-negative bacteria and are then extracted by the LptB2FG complex during the first step of LPS transport to the outer membrane. Here the authors present the LptB2FG structure, which supports an alternating lateral access mechanism for LPS extraction. |
format |
article |
author |
Haohao Dong Zhengyu Zhang Xiaodi Tang Neil G. Paterson Changjiang Dong |
author_facet |
Haohao Dong Zhengyu Zhang Xiaodi Tang Neil G. Paterson Changjiang Dong |
author_sort |
Haohao Dong |
title |
Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG |
title_short |
Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG |
title_full |
Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG |
title_fullStr |
Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG |
title_full_unstemmed |
Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG |
title_sort |
structural and functional insights into the lipopolysaccharide abc transporter lptb2fg |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/9f348f6efa4b41969dce2efed310a489 |
work_keys_str_mv |
AT haohaodong structuralandfunctionalinsightsintothelipopolysaccharideabctransporterlptb2fg AT zhengyuzhang structuralandfunctionalinsightsintothelipopolysaccharideabctransporterlptb2fg AT xiaoditang structuralandfunctionalinsightsintothelipopolysaccharideabctransporterlptb2fg AT neilgpaterson structuralandfunctionalinsightsintothelipopolysaccharideabctransporterlptb2fg AT changjiangdong structuralandfunctionalinsightsintothelipopolysaccharideabctransporterlptb2fg |
_version_ |
1718396665341149184 |