The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis

Background: Ulcerative colitis [UC] is an inflammatory disease of the colon with a relapsing-remitting course. Early diagnosis is crucial, and the presence of a screening test is of utmost importance.Bowel ultrasound could be used as a screening tool for UC. Aim of the work: To assess the diagnostic...

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Autores principales:	Ragab Mahmoud Ragab, Mohamed Heiza, Khaled Elmola, Mostafa M. Shakweer
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Materias:	ultrasound bowel ulcerative colitis inflammatory bowel disease colonoscopy Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9f399b5aba584bf798c322c297aa725d
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spelling	oai:doaj.org-article:9f399b5aba584bf798c322c297aa725d2021-12-02T14:33:24ZThe role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis2636-41742682-378010.21608/ijma.2020.45279.1188https://doaj.org/article/9f399b5aba584bf798c322c297aa725d2021-01-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_128764_c83845117d905428081ba39b1b092e69.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Ulcerative colitis [UC] is an inflammatory disease of the colon with a relapsing-remitting course. Early diagnosis is crucial, and the presence of a screening test is of utmost importance.Bowel ultrasound could be used as a screening tool for UC. Aim of the work: To assess the diagnostic accuracy of bowel ultrasound in detecting disease activity and severity in adult patients with UC, compared with Ileocolonoscopy as the reference standard. Patients and methods: This prospective study included 42 adult patients with an established UC diagnosis for at least six months. All patients were subjected to full inquiry about their disease history, complete clinical examination, laboratory investigations, colonoscopy, and bowel ultrasound of the abdomen with Doppler mapping. Results: Colonoscopy revealed that 41% in remission and 59% in an activity. Thirty patients had left-sided, and 12 had an extensive UC. White blood cells, platelet count, erythrocyte sedimentation rate, and C- reactive protein significantly increased in patients with activity versus remission. But, hemoglobin concentrations significantly decreased. Colonic wall thickness significantly increased in patients with activity versus remission [5.17±0.74 vs. 2.57±0.24, respectively]. Hypoechogenic or lost colonic wall pattern, enlarged mesenteric lymph nodes and Doppler colonic wall-flow significantly increased in cases with disease activity versus remission [32.0%, 24.0% and 72.0% vs 0.0%, 0.0% and 0.0% respectively]. Conclusion: Transabdominal bowel ultrasound had a beneficial role in diagnosing ulcerative colitis. It could be used as a screening tool for rapid diagnosis or follow up of treatment.Ragab Mahmoud RagabMohamed HeizaKhaled ElmolaMostafa M. ShakweerAl-Azhar University, Faculty of Medicine (Damietta)articleultrasoundbowelulcerative colitisinflammatory bowel diseasecolonoscopyMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 1, Pp 1119-1124 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	ultrasound bowel ulcerative colitis inflammatory bowel disease colonoscopy Medicine (General) R5-920
spellingShingle	ultrasound bowel ulcerative colitis inflammatory bowel disease colonoscopy Medicine (General) R5-920 Ragab Mahmoud Ragab Mohamed Heiza Khaled Elmola Mostafa M. Shakweer The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis
description	Background: Ulcerative colitis [UC] is an inflammatory disease of the colon with a relapsing-remitting course. Early diagnosis is crucial, and the presence of a screening test is of utmost importance.Bowel ultrasound could be used as a screening tool for UC. Aim of the work: To assess the diagnostic accuracy of bowel ultrasound in detecting disease activity and severity in adult patients with UC, compared with Ileocolonoscopy as the reference standard. Patients and methods: This prospective study included 42 adult patients with an established UC diagnosis for at least six months. All patients were subjected to full inquiry about their disease history, complete clinical examination, laboratory investigations, colonoscopy, and bowel ultrasound of the abdomen with Doppler mapping. Results: Colonoscopy revealed that 41% in remission and 59% in an activity. Thirty patients had left-sided, and 12 had an extensive UC. White blood cells, platelet count, erythrocyte sedimentation rate, and C- reactive protein significantly increased in patients with activity versus remission. But, hemoglobin concentrations significantly decreased. Colonic wall thickness significantly increased in patients with activity versus remission [5.17±0.74 vs. 2.57±0.24, respectively]. Hypoechogenic or lost colonic wall pattern, enlarged mesenteric lymph nodes and Doppler colonic wall-flow significantly increased in cases with disease activity versus remission [32.0%, 24.0% and 72.0% vs 0.0%, 0.0% and 0.0% respectively]. Conclusion: Transabdominal bowel ultrasound had a beneficial role in diagnosing ulcerative colitis. It could be used as a screening tool for rapid diagnosis or follow up of treatment.
format	article
author	Ragab Mahmoud Ragab Mohamed Heiza Khaled Elmola Mostafa M. Shakweer
author_facet	Ragab Mahmoud Ragab Mohamed Heiza Khaled Elmola Mostafa M. Shakweer
author_sort	Ragab Mahmoud Ragab
title	The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis
title_short	The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis
title_full	The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis
title_fullStr	The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis
title_full_unstemmed	The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis
title_sort	role of trans-abdominal ultrasound in assessing disease activity and severity in ulcerative colitis
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/9f399b5aba584bf798c322c297aa725d
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The role of Trans-abdominal Ultrasound in Assessing Disease Activity and Severity in Ulcerative Colitis

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