Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer’s disease

Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer’s disease

Abstract To characterize rod- and cone-pathway function in the 5xFAD mouse model of Alzheimer’s disease (AD) using the full-field electroretinogram (ERG). Dark-adapted (DA; rod-pathway) and light-adapted (LA; cone-pathway) ERGs were recorded from three-month-old 5xFAD and wild type (WT) mice. ERGs w...

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Bibliographic Details
Main Authors: J. Jason McAnany, Nathanael Matei, Yi-Fan Chen, Karen Liu, Jason C. Park, Mahnaz Shahidi
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/9f3da13689e44b65bc357740fe0f6c9a
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