Rod pathway and cone pathway retinal dysfunction in the 5xFAD mouse model of Alzheimer’s disease

Abstract To characterize rod- and cone-pathway function in the 5xFAD mouse model of Alzheimer’s disease (AD) using the full-field electroretinogram (ERG). Dark-adapted (DA; rod-pathway) and light-adapted (LA; cone-pathway) ERGs were recorded from three-month-old 5xFAD and wild type (WT) mice. ERGs w...

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Bibliographic Details
Main Authors: J. Jason McAnany, Nathanael Matei, Yi-Fan Chen, Karen Liu, Jason C. Park, Mahnaz Shahidi
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/9f3da13689e44b65bc357740fe0f6c9a
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